SCHEMBL6909139

SCHEMBL6909139

CO[SiH](CC(C)CCC1CCCCC1)OC

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.35
METAP1 P53582 1/20 0.35
METAP2 P50579 1/20 0.33
SIGMAR1 Q99720 2/20 0.31
HTT P42858 1/20 0.30
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6909519 1.00 CYP1A2 (0.35) CYP1A2METAP1METAP2SIGMAR1HTT
SCHEMBL6907780 1.00 CYP1A2 (0.35) CYP1A2METAP1METAP2SIGMAR1HTT
SCHEMBL6907687 0.98 METAP1 (0.33) CYP1A2METAP1METAP2
SCHEMBL6909508 0.95
SCHEMBL6902884 0.91 MAPT (0.30)
SCHEMBL6909264 0.83 CYP1A2 (0.37) CYP1A2METAP1METAP2
SCHEMBL6903203 0.83 CYP1A2 (0.37) CYP1A2METAP1METAP2
SCHEMBL6908993 0.83 CYP1A2 (0.37) CYP1A2METAP1METAP2
SCHEMBL6909523 0.81 METAP2 (0.35) CYP1A2METAP1METAP2
SCHEMBL28439521 0.81 METAP1 (0.41) CYP1A2METAP1METAP2SIGMAR1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1563119-A Olefin hydrocarbon polymerization catalyst, method of preparing olefinic polymer, and olefinic polymer IDEMITSU KOSAN CO (JP) 2005-01-12 CN disclosed
US-6689849-B1 Catalyst for bulk polymerization, catalyst for vapor phase polymerization, method of polymerization using these, and olefin polymer obtained with these IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2004-02-10 US disclosed
CN-1358200-A Catalyst for bulk polymerization, catalyst for vapor phase polymerization, method of polymerization using these and olefymer obtained with these IDEMITSU PETROCHEMICAL CO (JP) 2002-07-10 CN disclosed
EP-1188774-A1 CATALYST FOR BULK POLYMERIZATION, CATALYST FOR VAPOR PHASE POLYMERIZATION, METHOD OF POLYMERIZATION USING THESE, AND OLEFIN POLYMER OBTAINED WITH THESE IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2002-03-20 EP disclosed
CN-1293209-A Olefin polymerization catalyst, process for producing olefin polymer, and olefin polymer IDEMITSU KOSAN CO (JP) 2001-05-02 CN disclosed
EP-1094083-A2 Catalyst for olefin polymerization, method for producing olefin polymer, and olefin polymer IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2001-04-25 EP disclosed