SCHEMBL690921

SCHEMBL690921

CC1=C(C(C)(C)C)C([Zr](C)(C)(=[SiH2])C2C(C(C)(C)C)=C(C)c3c(-c4ccccc4)ccc(-c4ccccc4)c32)c2c(-c3ccccc3)ccc(-c3ccccc3)c21

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL690924 0.99
SCHEMBL690700 0.89
Hydrochloric Acid SCHEMBL690064 0.88
SCHEMBL691100 0.88 TSHR (0.30)
SCHEMBL689405 0.85 CNR1 (0.31)
SCHEMBL695973 0.78 DHFR (0.32)
Hydrochloric Acid SCHEMBL3056112 0.71 BRD4 (0.31)
SCHEMBL690443 0.70
Hydrochloric Acid SCHEMBL3061484 0.69 EDNRB (0.33)
Hydrochloric Acid SCHEMBL3078693 0.69 MEN1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2203486-B9 RACEMOSELECTIVE SYNTHESIS OF ANSA-METALLOCENE COMPOUNDS, ANSA-METALLOCENE COMPOUNDS, CATALYSTS COMPRISING THEM, PROCESS FOR PRODUCING AN OLEFIN POLYMER BY USE OF THE CATALYSTS, AND OLEFIN HOMO- AND COPOLYMERS LUMMUS NOVOLEN TECHNOLOGY GMBH (DE) 2012-08-01 EP claimed
EP-2203486-B1 RACEMOSELECTIVE SYNTHESIS OF ANSA-METALLOCENE COMPOUNDS, ANSA-METALLOCENE COMPOUNDS, CATALYSTS COMPRISING THEM, PROCESS FOR PRODUCING AN OLEFIN POLYMER BY USE OF THE CATALYSTS, AND OLEFIN HOMO- AND COPOLYMERS LUMMUS NOVOLEN TECHNOLOGY GMBH (DE) 2012-02-29 EP claimed