SCHEMBL6909276

SCHEMBL6909276

O=C(O)c1c(O)cc(O)c(O)c1C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.50
CA2 P00918 3/20 0.50
CA12 O43570 2/20 0.50
CA7 P43166 2/20 0.50
CA9 Q16790 2/20 0.50
CA14 Q9ULX7 2/20 0.50
MAPT P10636 2/20 0.50
DPP4 P27487 2/20 0.50
HPGD P15428 2/20 0.50
KDM4E B2RXH2 1/20 0.50
ALDH1A1 P00352 1/20 0.50
LMNA P02545 1/20 0.50
TP53 P04637 1/20 0.50
CA3 P07451 1/20 0.50
SELL P14151 1/20 0.50
SELP P16109 1/20 0.50
FUT4 P22083 1/20 0.50
CA4 P22748 1/20 0.50
CA6 P23280 1/20 0.50
MAPK1 P28482 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3515579 0.89 CA1 (0.55) CA1CA2CA12CA7CA9
SCHEMBL28062208 0.86 CYP3A4 (0.52) CA1CA2CA12CA7CA9
SCHEMBL29385781 0.84 CA1 (0.50) CA1CA2CA12CA7CA9
SCHEMBL3516889 0.84 CA1 (0.50) CA1CA2CA12CA7CA9
SCHEMBL9350983 0.83 FFAR1 (0.52) CA1CA2CA12CA7CA9
SCHEMBL7261612 0.80 CA1 (0.46) CA1CA2CA12CA7CA9
SCHEMBL28062216 0.80 THRB (0.50) CA1CA2CA12CA7CA9
SCHEMBL14761042 0.78 CYP3A4 (0.52) CA1CA2CA12CA7CA9
SCHEMBL21936695 0.77 KDM4E (0.46) CA1CA2CA12CA7CA9
SCHEMBL8736074 0.77 PTPN1 (0.45) CA1CA2CA12CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104726237-A Yellow-spot-removing dry cleaning agent SHANGHAI PENGGANG IND DEV CO LTD 2015-06-24 CN disclosed
US-6730810-B2 HOMOGENOUS MIXTURE COMPRISING ACID HALIDE WITH HYDROXY CARBOXYLIC ACIDS AND ANHYDRIDE; DISCOLORATION INHIBITION HUNTSMAN PETROCHEMICAL CORPORATION 2004-05-04 US disclosed
US-6603042-B2 Mixing acid halide and hydroxycarboxylic acid with maleic acid anhydride forming homogeneous solution having reduced tendency to discolor HUNTSMAN PETROCHEMICAL CORPORATION 2003-08-05 US disclosed
US-6593495-B1 Anhydride stabilization HUNTSMAN PETROCHEMICAL CORPORATION 2003-07-15 US disclosed
US-20030120089-A1 Anhydride stabilization HUNTSMAN PETROCHEMICAL CORPORATION 2003-06-26 US disclosed
EP-1144354-B1 ANHYDRIDE STABILIZATION HUNTSMAN SPEC CHEM CORP (US) 2003-05-14 EP disclosed
US-20030083522-A1 Anhydride stabilization HUNTSMAN PETROCHEMICAL CORPORATION 2003-05-01 US disclosed
EP-1144354-A1 ANHYDRIDE STABILIZATION HUNTSMAN PETROCHEMICAL CORPORATION (US) 2001-10-17 EP disclosed
WO-2000041991-A1 ANHYDRIDE STABILIZATION HUNTSMAN PETROCHEMICAL CORPORATION (US) 2000-07-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030120089-A1 Anhydride stabilization CA7, CA4, CA9 CA1 8/4885CA2 4/4885CA12 5/4885
US-20030083522-A1 Anhydride stabilization CA7, CA4, CA9 CA1 8/4885CA2 4/4885CA12 5/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.