Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.65 |
| ▸ | BLM | P54132 | 1/20 | 0.65 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | DAO | P14920 | 3/20 | 0.56 |
| ▸ | MAOB | P27338 | 3/20 | 0.49 |
| ▸ | PGR | P06401 | 4/20 | 0.48 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.45 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.45 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.45 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.45 |
| ▸ | B3GNT2 | Q9NY97 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6904350 | 0.80 | CYP1A2 (0.67) | CYP1A2MEN1KMT2ALMNACYP3A4 | |
| SCHEMBL31481931 | 0.79 | MAOB (0.64) | CYP1A2MEN1KMT2ALMNACYP3A4 | |
| SCHEMBL6907750 | 0.79 | MAOB (0.64) | CYP1A2MEN1KMT2ALMNACYP3A4 | |
| SCHEMBL4077298 | 0.79 | CYP1A2 (0.60) | CYP1A2MEN1KMT2ALMNACYP3A4 | |
| SCHEMBL8139335 | 0.79 | CYP1A2 (0.45) | CYP1A2MEN1KMT2ALMNACYP3A4 | |
| SCHEMBL7063351 | 0.79 | CYP1A2 (0.65) | CYP1A2MEN1KMT2ALMNACYP3A4 | |
| SCHEMBL612079 | 0.79 | CYP1A2 (1.00) | CYP1A2MEN1KMT2ALMNACYP3A4 | |
| SCHEMBL6799574 | 0.79 | CYP1A2 (0.65) | CYP1A2MEN1KMT2ALMNACYP3A4 | |
| SCHEMBL29701185 | 0.79 | CYP1A2 (1.00) | CYP1A2MEN1KMT2ALMNACYP3A4 | |
| SCHEMBL23997304 | 0.77 | PGR (0.56) | MEN1KMT2ALMNACYP3A4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004039409-A2 | COMPOSITION COMPRISING ACTIVATORS OF IK POTASSIUM CHANNELS AND CALCINEURIN ANTAGONISTS AND USE THEREOF | SWITCH BIOTECH AG (DE) | 2004-05-13 | — | — | WO | claimed |