SCHEMBL6909446

SCHEMBL6909446

CCCC[PH](c1ccccc1)(c1ccccc1)C(F)(F)C(F)CCCCCCC(F)(F)F

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CSNK1E P49674 1/20 0.32
CYSLTR2 Q9NS75 1/20 0.31
CYSLTR1 Q9Y271 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6910160 0.96 CSNK1E (0.34) CSNK1ECYSLTR2CYSLTR1
SCHEMBL6906826 0.80 MMP2 (0.33) CYSLTR2CYSLTR1
SCHEMBL6909443 0.71 GAA (0.34)
SCHEMBL6910156 0.69 GAA (0.34)
SCHEMBL5715696 0.68 CSNK1E (0.32) CSNK1E
SCHEMBL5715857 0.68 NPC1 (0.32)
SCHEMBL13525958 0.67 POLB (0.32)
SCHEMBL5716554 0.64 MMP2 (0.32) CYSLTR2CYSLTR1
SCHEMBL17092418 0.63 TSHR (0.36)
SCHEMBL6908724 0.62 MAPT (0.31) CSNK1E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6822057-B2 OLEFIN POLYMERIZATION CATALYST SYSTEM IS A REACTION PRODUCT OF A METALLOCENES AND A COCATALYST CONTAINING FLUOROARYL SUBSTITUTED SECONDARY AMINE OR PHSOPHINE COMPOUND AND AN ANION CONTAINING GROUP 13 ELEMENT WHICH IS NONCOORDINATIG EXXON MOBIL CHEMICAL PATENTS INC. 2004-11-23 US disclosed
US-6489480-B2 COORDINATION POLYMERIZATION CATALYST FOR ALPHA-OLEFINS EXXONMOBIL CHEMICAL PATENTS INC. 2002-12-03 US disclosed
US-20020115806-A1 Olefin polymerization catalysts derived from Group-15 cationic compounds and processes using them EXXONMOBIL CHEMICAL PATENTS INC. 2002-08-22 US disclosed