Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.72 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.72 |
| ▸ | TSHR | P16473 | 2/20 | 0.72 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.72 |
| ▸ | THPO | P40225 | 2/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.72 |
| ▸ | GLA | P06280 | 1/20 | 0.72 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.72 |
| ▸ | NPC1 | O15118 | 1/20 | 0.72 |
| ▸ | NPY1R | P25929 | 1/20 | 0.72 |
| ▸ | HTT | P42858 | 1/20 | 0.72 |
| ▸ | NPY2R | P49146 | 1/20 | 0.72 |
| ▸ | RAB9A | P51151 | 1/20 | 0.72 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.72 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.69 |
| ▸ | TP53 | P04637 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29617913 | 1.00 | LMNA (0.72) | LMNASLC29A1TSHRNFKB1THPO | |
| SCHEMBL27986516 | 1.00 | LMNA (0.72) | LMNASLC29A1TSHRNFKB1THPO | |
| SCHEMBL17889837 | 1.00 | LMNA (0.72) | LMNASLC29A1TSHRNFKB1THPO | |
| SCHEMBL313413 | 1.00 | LMNA (0.72) | LMNASLC29A1TSHRNFKB1THPO | |
| SCHEMBL17301042 | 1.00 | LMNA (0.72) | LMNASLC29A1TSHRNFKB1THPO | |
| SCHEMBL9945526 | 1.00 | LMNA (0.72) | LMNASLC29A1TSHRNFKB1THPO | |
| SCHEMBL19485512 | 1.00 | LMNA (0.72) | LMNASLC29A1TSHRNFKB1THPO | |
| SCHEMBL233209 | 1.00 | LMNA (0.72) | LMNASLC29A1TSHRNFKB1THPO | |
| SCHEMBL21953578 | 1.00 | LMNA (0.72) | LMNASLC29A1TSHRNFKB1THPO | |
| SCHEMBL233208 | 1.00 | LMNA (0.72) | LMNASLC29A1TSHRNFKB1THPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040077569-A1 | Antisense modulation of Notch (Drosophila) homolog 4 expression | ISIS PHARMACEUTICALS INC. | 2004-04-22 | — | — | US | disclosed |
| US-20040077084-A1 | Antisense modulation of histone deacetylase 4 expression | ISIS PHARMACEUTICALS INC. | 2004-04-22 | — | — | US | disclosed |
| US-20030211611-A1 | Antisense modulation of estrogen receptor alpha expression | DOBIE KENNETH W (US) | 2003-11-13 | — | — | US | disclosed |