Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5937055 | 0.89 | PLK1 (0.40) | SMN1; SMN2 | |
| SCHEMBL7746754 | 0.78 | PLK1 (0.47) | SMN1; SMN2 | |
| SCHEMBL16178694 | 0.74 | RPS6KA3 (0.35) | — | |
| SCHEMBL6844754 | 0.71 | PLK1 (0.51) | — | |
| SCHEMBL15987137 | 0.70 | SMN1; SMN2 (0.32) | SMN1; SMN2 | |
| SCHEMBL15221438 | 0.70 | SMN1; SMN2 (0.36) | SMN1; SMN2 | |
| SCHEMBL1688473 | 0.70 | TYRO3 (0.31) | SMN1; SMN2 | |
| SCHEMBL2340438 | 0.69 | PLK1 (0.59) | — | |
| SCHEMBL21491837 | 0.68 | MAPK1 (0.35) | SMN1; SMN2 | |
| SCHEMBL3546500 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011079114-A1 | PTERIDINONES AS INHIBITORS OF POLO - LIKE KINASE | ELAN PHARMACEUTICALS, INC. (US) | 2011-06-30 | — | — | WO | disclosed |