Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | CA12 | O43570 | 6/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 4/20 | 0.38 |
| ▸ | CA9 | Q16790 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14654893 | 0.80 | FNTA (0.53) | TSHRCA12CA14KMT2AMEN1 | |
| SCHEMBL5265771 | 0.80 | TSHR (0.52) | TSHRCA12CA14KMT2AMEN1 | |
| SCHEMBL9026191 | 0.78 | TSHR (0.44) | TSHRCA12CA14KMT2AMEN1 | |
| SCHEMBL3265255 | 0.77 | TSHR (0.48) | TSHRCA12CA14KMT2AMEN1 | |
| SCHEMBL27261915 | 0.75 | TSHR (0.46) | TSHRCA12CA14KMT2AMEN1 | |
| SCHEMBL11922841 | 0.73 | TSHR (0.55) | TSHRCA12CA14KMT2AMEN1 | |
| SCHEMBL28473081 | 0.72 | TSHR (0.43) | TSHRCA12CA14KMT2AMEN1 | |
| SCHEMBL4060095 | 0.71 | TSHR (0.67) | TSHRCA12CA14KMT2AMEN1 | |
| SCHEMBL29000521 | 0.71 | TSHR (0.67) | TSHRCA12CA14KMT2AMEN1 | |
| SCHEMBL27522 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1075463-B1 | CONVERSION OF A HYDROXY GROUP IN CERTAIN ALCOHOLS INTO A FLUOROSULFONATE ESTER OR A TRIFLUOROMETHYLSULFONATE ESTER | LOEWENTHAL HANS JACOB EDGAR (IL) | 2004-06-16 | — | — | EP | disclosed |
| US-6395918-B1 | Conversion of a hydroxy group in certain alcohols into a fluorosulfonate ester or a trifluoromethylsulfonate ester | LOEWENTHAL HANS JACOB EDGAR (IL) | 2002-05-28 | — | — | US | disclosed |