Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2360614 | 0.87 | TSHR (0.64) | TSHRALDH1A1CYP3A4HPGDTHRB | |
| SCHEMBL15901344 | 0.84 | TSHR (0.59) | TSHRALDH1A1CYP3A4HPGDTHRB | |
| SCHEMBL322104 | 0.77 | TSHR (0.57) | TSHRALDH1A1CYP3A4HPGDTHRB | |
| SCHEMBL13945622 | 0.76 | TSHR (1.00) | TSHRALDH1A1CYP3A4HPGDTHRB | |
| SCHEMBL322713 | 0.76 | TSHR (1.00) | TSHRALDH1A1CYP3A4HPGDTHRB | |
| SCHEMBL8493780 | 0.76 | TSHR (1.00) | TSHRALDH1A1CYP3A4HPGDTHRB | |
| SCHEMBL9101988 | 0.76 | TSHR (1.00) | TSHRALDH1A1CYP3A4HPGDTHRB | |
| SCHEMBL20873747 | 0.76 | TSHR (1.00) | TSHRALDH1A1CYP3A4HPGDTHRB | |
| SCHEMBL33725 | 0.76 | TSHR (1.00) | TSHRALDH1A1CYP3A4HPGDTHRB | |
| SCHEMBL13283404 | 0.76 | TSHR (1.00) | TSHRALDH1A1CYP3A4HPGDTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-62292774-A | — | — | None | — | — | JP | disclosed |
| US-20040259992-A1 | Two-component adhesion promoter combination of an unsaturated alkoxysilane and a mercaptoalkyl alkoxysilane, for use in dental prostheses | 3M ESPE AG (DE) | 2004-12-23 | — | — | US | disclosed |
| EP-1360245-B1 | ADHESIVES FOR METAL-POLYMER COMPOSITES | 3M ESPE AG (DE) | 2004-07-14 | — | — | EP | disclosed |
| EP-1360245-A1 | ADHESIVES FOR METAL-POLYMER COMPOSITES | 3M Espe AG (DE) | 2003-11-12 | — | — | EP | disclosed |
| WO-2002072711-A1 | ADHESIVES FOR METAL-POLYMER COMPOSITES | 3M ESPE AG (DE) | 2002-09-19 | — | — | WO | disclosed |
| JP-S62292774-A | TRIAZINTHIOL GROUP-CONTAINING (METH)ACRYLIC ESTER | KURARAY CO LTD | 1987-12-19 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040259992-A1 | Two-component adhesion promoter combination of an unsaturated alkoxysilane and a mercaptoalkyl alkoxysilane, for use in dental prostheses | ITGA2, ITGB2, ITGA2B | TSHR 3882/4885ALDH1A1 453/4885CYP3A4 4422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.