Sugi Predict

Sugi Predict / Targets / ITGA2

ITGA2

Integrin alpha-2 · P17301 · ITGA2 on Sugi Atlas →

6,274 patent compounds predicted against ITGA2, 3,943 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL1487417 SCHEMBL1487417 1.00 7/20
SCHEMBL3113470 SCHEMBL3113470 1.00 7/20
SCHEMBL3116856 SCHEMBL3116856 1.00 7/20
SCHEMBL1487440 SCHEMBL1487440 0.90 7/20
SCHEMBL1487388 SCHEMBL1487388 0.89 7/20
SCHEMBL1487415 SCHEMBL1487415 0.89 7/20
SCHEMBL1487432 SCHEMBL1487432 0.89 7/20
SCHEMBL1487392 SCHEMBL1487392 0.86 7/20
SCHEMBL1487400 SCHEMBL1487400 0.85 7/20
SCHEMBL1487445 SCHEMBL1487445 0.85 7/20
SCHEMBL1487437 SCHEMBL1487437 0.84 7/20
SCHEMBL1487435 SCHEMBL1487435 0.84 7/20
SCHEMBL1487447 SCHEMBL1487447 0.83 7/20
SCHEMBL1487451 SCHEMBL1487451 0.82 7/20
SCHEMBL1487411 SCHEMBL1487411 0.81 7/20
SCHEMBL1487436 SCHEMBL1487436 0.81 7/20
SCHEMBL1487361 SCHEMBL1487361 0.81 7/20
SCHEMBL3112064 SCHEMBL3112064 0.81 7/20
SCHEMBL1487347 SCHEMBL1487347 0.78 7/20
SCHEMBL1487439 SCHEMBL1487439 0.77 7/20

Clinical trials — most relevant to ITGA2 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
The Outcomes of ICSI Cycles With and Without Letrozole PHASE4UNKNOWN
68 Ga-NODAGA-E[c(RGDγK)]2: Positron Emission Tomography Tracer for Imaging of Angiogenesis in Ischemic Heart Disease PHASE2UNKNOWN
A Gene Therapy Trial to Evaluate the Safety and Efficacy of RP-L201 in Subjects With Leukocyte Adhesion Deficiency-I PHASE1WITHDRAWN
Safety/Biomarker Study of CNTO 95 and Avastin in Solid Tumors PHASE1COMPLETED
A Study of 99mTc-3PRGD2 Injection in Healthy Volunteers PHASE1COMPLETED
68Ga-BNOTA-PRGD2 PET/CT in Patients With Rheumatoid Arthritis EARLY_PHASE1UNKNOWN
68Ga-NOTA-PRGD2 PET/CT in Patients With Lung Injury and Pulmonary Fibrosis EARLY_PHASE1UNKNOWN
68Ga-BNOTA-PRGD2 PET/CT in Diagnosis and Evaluation of Glioma EARLY_PHASE1UNKNOWN
68Ga-BNOTA-PRGD2 PET/CT in Evaluation of Stroke EARLY_PHASE1UNKNOWN
177Lu-AB-3PRGD2 in Patients With Integrin αVβ3 Positive Tumors EARLY_PHASE1RECRUITING
68Ga-BNOTA-PRGD2 PET/CT in Evaluation of Myocardial Infarction EARLY_PHASE1UNKNOWN
68Ga-BNOTA-PRGD2 PET/CT in Healthy Volunteers and Lung Cancer Patients EARLY_PHASE1UNKNOWN
99mTc-3PRGD2 SPECT/CT in Rheumatoid Arthritis Patients EARLY_PHASE1COMPLETED
Anti-αIIbβ3 Immunization in Glanzmann Thrombasthenia: Prevalence and Associated Risk Factors: Thrombasthenia Anti-αIIbβ3 Antibodies Study (TAAS) nanCOMPLETED
Angiogenesis and Fibrosis in Aortic Stenosis nanCOMPLETED
In-vivo Thrombus Imaging With 18F-GP1, a Novel Platelet PET Radiotracer nanCOMPLETED
Clinical Study of 18F-FAPI-RGD in Ovarian Cancer nanCOMPLETED
Angiogenesis and Fibrosis in Myocardial Infarction nanCOMPLETED
The Role of Platelet Surface α2β1 Integrin Expression as a Risk Factor in Thrombotic and/or Bleeding Complications nanCOMPLETED
IMaging Pilot Study of the αvβ6 Integrin Radiotracer [18F]-A20FMDV2 in PAtients With Solid Cancer Types nanCOMPLETED
ITGA2b and SELP Expression in Cancer Pancreas and Biliary Tract Cancer nanUNKNOWN
The Role of CD4+ T Cell Subsets in the Mechanism of Action of Vedolizumab in Ulcerative Colitis nanUNKNOWN
Clinical Pattern of Glanzemnn Thrombathenia in Children Attending Assiut University Children Hospital nanNOT_YET_RECRUITING
Hypolipemic Treatment in Acute Coronary Syndrome (ACS): Antithrombotic Effects nanUNKNOWN
The Development of a Clinical Test to Assess the Inflammatory Phenotype of Asthma nanCOMPLETED
Potential Role of microRNA 410 and BIRC7 Pathways in Recurrent Spontaneous Miscarriage nanCOMPLETED
The Role of the Novel 99mTc-NC100692 Tracer in Patients at High Risk or Known Breast Cancer nanUNKNOWN
CancerenD24 Screening as an Aid to the Clinician for the Diagnosis of Cancer nanRECRUITING
Early Regenerative Intervention for Post-Traumatic Osteoarthritis nanUNKNOWN
An Imaging Study in ER Negative Breast Cancer by Targeting αvβ6 nanWITHDRAWN

Related proteins — ESM-2 sequence neighbours (a ITGA2 binder may also engage these)

ProteinNameSimilarity
Q62469 — 1.000 Q62469 →
P53710 — 1.000 P53710 →
P61622 — 0.992 P61622 →
ITGAM Integrin alpha-M 0.989 landscape →
Q13797 — 0.988 Q13797 →
Q9UKX5 — 0.988 Q9UKX5 →
P38570 — 0.987 P38570 →
P05555 — 0.987 P05555 →
E1BFX5 — 0.986 E1BFX5 →
ITGAL Integrin alpha-L 0.986 landscape →
Q00651 — 0.985 Q00651 →
P61625 — 0.985 P61625 →
Q9QXH4 — 0.985 Q9QXH4 →
B8JK39 — 0.985 B8JK39 →
ITGA8 Integrin alpha-8 [Cleaved into: Integrin alph 0.984 landscape →
ITGA4 Integrin alpha-4 0.984 landscape →
Q60677 — 0.983 Q60677 →
A2ARA8 — 0.983 A2ARA8 →
P26009 — 0.982 P26009 →
Q62470 — 0.979 Q62470 →
Q13349 — 0.979 Q13349 →
Q3V0T4 — 0.978 Q3V0T4 →
ITGAV Integrin alpha-V 0.978 landscape →
P43406 — 0.977 P43406 →
P24063 — 0.977 P24063 →
P18614 — 0.976 P18614 →
P20702 — 0.976 P20702 →
P26006 — 0.975 P26006 →
P17852 — 0.974 P17852 →
F1MMS9 — 0.974 F1MMS9 →