Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25637980 | 0.81 | TDP1 (0.56) | TDP1GPR84SMN1; SMN2FOLH1CA2 | |
| SCHEMBL2231042 | 0.81 | TDP1 (0.62) | TDP1GPR84SMN1; SMN2FOLH1CHRM1 | |
| SCHEMBL28522123 | 0.79 | TDP1 (0.39) | TDP1CA2MAPK1CHRM1AKR1A1 | |
| Ethane SCHEMBL27124138 | 0.79 | TDP1 (0.59) | TDP1GPR84SMN1; SMN2FOLH1 | |
| SCHEMBL20564459 | 0.78 | TDP1 (0.52) | TDP1GPR84SMN1; SMN2FOLH1CA2 | |
| SCHEMBL25637958 | 0.77 | TDP1 (0.46) | TDP1GPR84FOLH1CHRM1AKR1A1 | |
| SCHEMBL27965404 | 0.77 | FOLH1 (0.48) | TDP1GPR84FOLH1CA2MAPK1 | |
| SCHEMBL27682479 | 0.76 | FOLH1 (0.47) | TDP1GPR84FOLH1CA2MAPK1 | |
| SCHEMBL14359807 | 0.75 | CACNA2D1 (0.43) | TDP1GPR84SMN1; SMN2FOLH1CHRM1 | |
| SCHEMBL13696847 | 0.74 | GPR84 (0.58) | TDP1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6818583-B1 | HIGH YIELDS AND HIGH ISOTACTIC INDEX; COMPRISING MG, TI, HALOGEN AND A SUCCINATE ELECTRON DONOR | BASELL POLIOLEFINE ITALIA S.P.A. (IT) | 2004-11-16 | — | — | US | disclosed |