Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 2/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.51 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.51 |
| ▸ | GRM5 | P41594 | 5/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CASP1 | P29466 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16937189 | 0.90 | GRM5 (0.51) | KMT2AMEN1GRM5ESR1RAB9A | |
| SCHEMBL13433471 | 0.90 | GRM5 (0.51) | KMT2AMEN1GRM5ESR1RAB9A | |
| SCHEMBL7678431 | 0.87 | ESR1 (0.58) | KMT2AMEN1GRM5ESR1ALDH1A1 | |
| SCHEMBL2624619 | 0.86 | GRM5 (0.46) | KMT2AMEN1GRM5ESR1ALDH1A1 | |
| SCHEMBL16927161 | 0.84 | GRM5 (0.54) | KMT2AMEN1GRM5ESR1RAB9A | |
| SCHEMBL29842698 | 0.84 | ESR1 (0.67) | KMT2AMEN1USP2GRM5ESR1 | |
| SCHEMBL28505830 | 0.84 | ESR1 (0.67) | KMT2AMEN1USP2GRM5ESR1 | |
| SCHEMBL3447114 | 0.84 | GRM5 (0.46) | KMT2AMEN1GRM5ESR1RAB9A | |
| SCHEMBL10000450 | 0.84 | MAPK1 (0.53) | KMT2AMEN1USP2KEAP1NFE2L2 | |
| SCHEMBL13433467 | 0.84 | GRM5 (0.46) | KMT2AMEN1GRM5ESR1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0966493-A4 | REDUCED TEMPERATURE CURING OF ACETYLENIC POLYMERS | COMMW SCIENT IND RES ORG (AU) | 2004-04-21 | — | — | EP | disclosed |
| US-6344523-B1 | POLYIMIDES | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION OF CAMPBELL (AU) | 2002-02-05 | — | — | US | disclosed |
| EP-0966493-A1 | REDUCED TEMPERATURE CURING OF ACETYLENIC POLYMERS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1999-12-29 | — | — | EP | disclosed |
| WO-1998040422-A1 | REDUCED TEMPERATURE CURING OF ACETYLENIC POLYMERS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1998-09-17 | — | — | WO | disclosed |