Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HMGCR | P04035 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20182814 | 0.81 | TSHR (0.38) | TSHRALDH1A1CYP2D6CYP2C19HIF1A | |
| SCHEMBL16675272 | 0.76 | TSHR (0.38) | TSHRALDH1A1CYP2D6CYP2C19HIF1A | |
| Bicarbonate SCHEMBL2938234 | 0.72 | TSHR (0.33) | TSHRALDH1A1CYP2D6CYP2C19HIF1A | |
| SCHEMBL8356639 | 0.70 | ALDH1A1 (0.34) | TSHRALDH1A1CYP2D6CYP2C19HIF1A | |
| Bicarbonate SCHEMBL26105671 | 0.70 | TSHR (0.41) | TSHRALDH1A1CYP2D6CYP2C19HIF1A | |
| SCHEMBL1743650 | 0.69 | TSHR (0.42) | TSHRALDH1A1CYP2D6CYP2C19HIF1A | |
| SCHEMBL85014 | 0.69 | TSHR (0.42) | TSHRALDH1A1CYP2D6CYP2C19HIF1A | |
| SCHEMBL17376853 | 0.69 | TSHR (0.42) | TSHRALDH1A1CYP2D6CYP2C19HIF1A | |
| SCHEMBL14831849 | 0.69 | TSHR (0.42) | TSHRALDH1A1CYP2D6CYP2C19HIF1A | |
| SCHEMBL2221670 | 0.69 | CYP2C19 (0.46) | TSHRALDH1A1CYP2D6CYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918802-B2 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | BASELL TECHNOLOGY CO BV (NL) | 2004-10-06 | — | — | EP | disclosed |
| EP-0918802-B1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | BASELL TECHNOLOGY CO BV (NL) | 2001-11-14 | — | — | EP | disclosed |
| US-6294497-B1 | COMPRISING A TITANIUM COMPOUND, HAVING AT LEAST A TI-HALOGEN BOND AND AN ELECTRON DONER WHICH MAY BE A SUBSTITUTED MALONIC DIESTER, A 1,3-DIETHER OR A SILOXY COMPOUND SUPPORTED ON A MG HALIDE | MONTELL TECHNOLOGY COMPANY BV (NL) | 2001-09-25 | — | — | US | disclosed |
| EP-0918802-A2 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | Montell Technology Company bv (NL) | 1999-06-02 | — | — | EP | disclosed |
| WO-1998056830-A2 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | MONTELL TECHNOLOGY COMPANY B.V. (NL) | 1998-12-17 | — | — | WO | disclosed |