Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6910546 | 1.00 | PDE8B (0.68) | PDE8BPDE8A | |
| SCHEMBL6910407 | 0.84 | PDE8B (0.72) | PDE8B | |
| SCHEMBL6909028 | 0.84 | PDE8B (0.72) | PDE8B | |
| SCHEMBL6909035 | 0.83 | PDE8B (0.71) | PDE8BPDE8A | |
| SCHEMBL6910234 | 0.79 | PDE8B (0.68) | PDE8BPDE8A | |
| SCHEMBL6909462 | 0.71 | PDE8B (1.00) | PDE8BPDE8A | |
| SCHEMBL6910946 | 0.71 | PDE8B (1.00) | PDE8BPDE8A | |
| SCHEMBL6910646 | 0.71 | PDE8B (0.69) | PDE8BPDE8A | |
| SCHEMBL6909572 | 0.69 | PDE8B (1.00) | PDE8BPDE8A | |
| SCHEMBL30979663 | 0.64 | MET (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011058478-A1 | SUBSTITUTED TRIAZOLOPYRIMIDINES AS PDE8 INHIBITORS | PFIZER INC. (US) | 2011-05-19 | — | — | WO | disclosed |