Sugi Predict

Sugi Predict / Compounds / SCHEMBL691101

SCHEMBL691101

SCHEMBL691101

CCOC(=O)c1csc(Cl)n1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RAB9A P51151 9/20 0.64
▸ NPC1 O15118 7/20 0.64
▸ MAPT P10636 6/20 0.64
▸ ALDH1A1 P00352 3/20 0.64
▸ MEN1 O00255 1/20 0.64
▸ KMT2A Q03164 1/20 0.64
▸ CYP1A2 P05177 2/20 0.57
▸ CYP2C19 P33261 1/20 0.57
▸ SMN1; SMN2 Q16637 5/20 0.55
▸ GAA P10253 2/20 0.55
▸ POLB P06746 1/20 0.54
▸ PKM P14618 1/20 0.54
▸ NPSR1 Q6W5P4 1/20 0.54
▸ RXFP1 Q9HBX9 1/20 0.54
▸ EGFR P00533 1/20 0.52
▸ HSP90AA1 P07900 3/20 0.51
▸ MAPK1 P28482 1/20 0.51
▸ L3MBTL1 Q9Y468 1/20 0.50
▸ HPGD P15428 1/20 0.49
▸ TSHR P16473 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8478922 0.86 RAB9A (0.50) RAB9ANPC1MAPTALDH1A1MEN1
SCHEMBL10465943 0.83 MAPT (0.45) RAB9ANPC1MAPTALDH1A1MEN1
SCHEMBL13144514 0.82 MAPT (0.70) RAB9ANPC1MAPTALDH1A1MEN1
SCHEMBL914552 0.82 RAB9A (0.68) RAB9ANPC1MAPTALDH1A1MEN1
SCHEMBL24682625 0.81 MAPT (0.43) RAB9ANPC1MAPTALDH1A1MEN1
SCHEMBL285573 0.81 RAB9A (0.66) RAB9ANPC1MAPTALDH1A1MEN1
SCHEMBL1438508 0.81 RAB9A (0.66) RAB9ANPC1MAPTALDH1A1MEN1
SCHEMBL9454202 0.81 RAB9A (0.66) RAB9ANPC1MAPTALDH1A1MEN1
SCHEMBL163667 0.81 RAB9A (0.66) RAB9ANPC1MAPTALDH1A1MEN1
SCHEMBL19208916 0.81 RAB9A (0.66) RAB9ANPC1MAPTALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 254 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026099594-A1 THERAPEUTIC BIFUNCTIONAL AGENTS INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) 2026-05-15 — — WO disclosed
US-12570648-B2 6,7-dihydro-5H-pyrido[2,3-c]pyridazine derivatives and related compounds as Bcl-xL protein inhibitors and pro-apoptotic agents for treating cancer LES LABORATOIRES SERVIER (FR) 2026-03-10 — — US disclosed
EP-4647433-A1 SHP2 INHIBITOR AND USES THEREOF Kanaph Therapeutics Inc. (KR) 2025-11-12 — — EP disclosed
US-20250326764-A1 INHIBITORS OF THE MENIN-MLL INTERACTION VITAE PHARMACEUTICALS LLC (US) 2025-10-23 — — US disclosed
US-20250223285-A1 NOVEL HETEROCYCLIC DERIVATIVES USEFUL AS SHP2 INHIBITORS JACOBIO PHARMACEUTICALS CO LTD (CN) 2025-07-10 — — US disclosed
US-20250197387-A1 BCL-XL DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. 2025-06-19 — — US disclosed
US-12312359-B2 Inhibitors of the menin-MLL interaction VITAE PHARMACEUTICALS, LLC (US) 2025-05-27 — — US disclosed
CN-115996924-B Substituted pyrazolyl compounds and methods of use thereof 诺华医药股份公司 2025-03-07 — — CN disclosed
CN-113874363-B Protein tyrosine phosphatase inhibitors ARRAY生物制药公司 2024-11-12 — — CN disclosed
CN-113493440-B Salt of nitrogen-containing heteroaromatic derivative and crystal form thereof 上海翰森生物医药科技有限公司 2024-08-23 — — CN disclosed
WO-1997003976-A1 SEMICARBAZONE DERIVATIVES AND PESTICIDES NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1997-02-06 — — WO disclosed
US-5498630-A SUBSTITUTED BENZOTHIOPHENECARBOXAMIDES MONSANTO COMPANY (US) 1996-03-12 — — US disclosed
US-5395845-A Insecticides ROUSSEL-UCLAF (FR) 1995-03-07 — — US disclosed
CN-1085221-A Bactericide for preventing and treating plant take-all disease MONSANTO CO (US) 1994-04-13 — — CN disclosed
WO-1993007751-A1 FUNGICIDES FOR THE CONTROL OF TAKE-ALL DISEASE OF PLANTS MONSANTO COMPANY (US) 1993-04-29 — — WO disclosed
EP-0538231-A1 Fungicides for the control of take-all disease of plants MONSANTO COMPANY (US) 1993-04-21 — — EP disclosed
US-4933355-A ALDOSE REDUCTASE INHIBITORS SANKYO COMPANY LIMITED (JP) 1990-06-12 — — US disclosed
EP-0337819-A1 Thiazole derivatives, their preparation and their use in the treatment of diabetes complications Sankyo Company Limited (JP) 1989-10-18 — — EP disclosed
US-4501894-A Heterocyclic alcohols and their derivatives ROUSSEL UCLAF (FR) 1985-02-26 — — US disclosed
US-4450169-A PESTICIDES; NEMATOCIDES; FUNGICIDES; MITICIDES; REPELLANTS ROUSSEL UCLAF (FR) 1984-05-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250223285-A1 NOVEL HETEROCYCLIC DERIVATIVES USEFUL AS SHP2 INHIBITORS PTPN5, PTPN1, PTPRJ RAB9A 1131/4885NPC1 3191/4885MAPT 4283/4885
US-12312359-B2 Inhibitors of the menin-MLL interaction MLLT1, MEN1, MLLT3 RAB9A 2372/4885NPC1 3336/4885MAPT 1447/4885
US-12570648-B2 6,7-dihydro-5H-pyrido[2,3-c]pyridazine derivatives and related compounds as Bcl-xL protein inhibitors and pro-apoptotic agents for treating cancer BCOR, BCL2A1, BAK1 RAB9A 3362/4885NPC1 1398/4885MAPT 4819/4885
US-20250197387-A1 BCL-XL DEGRADERS AND USES THEREOF XIAP, BCL2L1, BCL2L10 RAB9A 1966/4885NPC1 4285/4885MAPT 2754/4885
US-20250326764-A1 INHIBITORS OF THE MENIN-MLL INTERACTION MLLT1, MEN1, MLLT3 RAB9A 2372/4885NPC1 3336/4885MAPT 1447/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.