Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.61 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.37 |
| ▸ | KDM5A | P29375 | 2/20 | 0.36 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | DGKA | P23743 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | ICMT | O60725 | 1/20 | 0.34 |
| ▸ | ALB | P02768 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.33 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1336548 | 1.00 | TSHR (0.61) | TSHRTHRBDNM1KDM5APHF8 | |
| SCHEMBL7103852 | 1.00 | TSHR (0.61) | TSHRTHRBDNM1KDM5APHF8 | |
| SCHEMBL14957359 | 0.98 | TSHR (0.58) | TSHRTHRBDNM1KDM5APHF8 | |
| SCHEMBL3278480 | 0.93 | TSHR (0.55) | TSHRTHRBDNM1KDM5APHF8 | |
| SCHEMBL830218 | 0.85 | TSHR (0.48) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL2832317 | 0.85 | TSHR (0.69) | TSHRTHRBDNM1KDM5APHF8 | |
| SCHEMBL10526650 | 0.85 | TSHR (0.69) | TSHRTHRBDNM1KDM5APHF8 | |
| SCHEMBL6914198 | 0.85 | TSHR (0.69) | TSHRTHRBDNM1KDM5APHF8 | |
| SCHEMBL12346282 | 0.85 | TSHR (0.69) | TSHRTHRBDNM1KDM5APHF8 | |
| SCHEMBL1336680 | 0.85 | TSHR (0.80) | TSHRTHRBDNM1KDM5APHF8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0979836-B1 | Paint of high weather resistance | TAISEI CHEMICAL IND LTD (JP) | 2004-12-15 | — | — | EP | disclosed |
| US-6248828-B1 | MODIFIED POLYURETHANES | TAISEI CHEMICAL INDUSTRIES, LTD. (JP) | 2001-06-19 | — | — | US | disclosed |
| EP-0979836-A1 | Paint of high weather resistance | Taisei Chemical Industries Ltd (JP) | 2000-02-16 | — | — | EP | disclosed |