SCHEMBL830218

SCHEMBL830218

C=C(C)C(=O)OCN(CCC)CCC

nearest known ligand 0.48

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.48
THRB P10828 1/20 0.46
ALDH1A1 P00352 5/20 0.39
CA12 O43570 1/20 0.34
CA2 P00918 1/20 0.34
CA9 Q16790 1/20 0.34
POLB P06746 1/20 0.31
APEX1 P27695 1/20 0.31
HTT P42858 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
LMNA P02545 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3278480 0.89 TSHR (0.55) TSHRTHRBALDH1A1CA12CA9
SCHEMBL14957359 0.87 TSHR (0.58) TSHRTHRBALDH1A1CA12CA9
SCHEMBL7103852 0.85 TSHR (0.61) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL1336548 0.85 TSHR (0.61) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL6911057 0.85 TSHR (0.61) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL21714531 0.84 THRB (0.50) TSHRTHRBALDH1A1CA12CA2
SCHEMBL284420 0.83 THRB (0.48) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL23530338 0.82 TSHR (0.47) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL21714569 0.82 TSHR (0.56) TSHRTHRBALDH1A1CA12CA2
SCHEMBL345460 0.82 TSHR (0.56) TSHRTHRBALDH1A1CA12CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115124669-A Preparation method and application of linear block copolymer nano-carrier with double-carrier genes and medicines 北京化工大学 2022-09-30 CN disclosed
US-20130129392-A1 DEVELOPER CARRYING MEMBER AND DEVELOPING UNIT CANON KABUSHIKI KAISHA (JP) 2013-05-23 US disclosed
US-8142971-B2 Electrostatic charge developer, electrostatic charge image developer cartridge, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2012-03-27 US disclosed
US-20090245858-A1 ELECTROSTATIC CHARGE DEVELOPER, ELECTROSTATIC CHARGE IMAGE DEVELOPER CARTRIDGE, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2009-10-01 US disclosed
EP-1095785-B1 INK-JET RECORDING SHEET TOMOEGAWA PAPER CO LTD (JP) 2005-11-23 EP disclosed
US-6565952-B1 Preventive effect on overall degradation by light such as degradation of image clarity, and decrease in density or change TOMOEGAWA PAPER CO., LTD. (JP) 2003-05-20 US disclosed
EP-1095785-A1 INK-JET RECORDING SHEET AND RESIN COMPOSITION FOR INK-JET RECORDING MEDIUM Tomoegawa Paper Co. Ltd. (JP) 2001-05-02 EP disclosed