Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.32 |
| ▸ | CNR2 | P34972 | 4/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6914629 | 0.91 | — | — | |
| SCHEMBL17196190 | 0.80 | HTR2C (0.32) | HTR2ATHRBTHRAHTR2CHTT | |
| SCHEMBL6911923 | 0.80 | PTGS2 (0.35) | HTR2APTGS2CYP3A4DRD2SLC6A2 | |
| SCHEMBL6914464 | 0.78 | S1PR1 (0.33) | L3MBTL1S1PR1NPC1SMN1; SMN2 | |
| SCHEMBL17108422 | 0.76 | TSHR (0.34) | HTR2AHTR2CHTTMAPTMAPK1 | |
| SCHEMBL6907317 | 0.76 | RARB (0.44) | HTR2APTGS2CYP3A4DRD2SLC6A2 | |
| SCHEMBL6912686 | 0.75 | RARB (0.37) | HTR2APTGS2CYP3A4DRD2SLC6A2 | |
| SCHEMBL6912143 | 0.74 | CSNK2A1 (0.33) | CNR1CNR2HTR2AHTR2CL3MBTL1 | |
| SCHEMBL18006905 | 0.71 | — | — | |
| SCHEMBL20819699 | 0.71 | RARB (0.37) | HTR2ATHRBHTTMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1223210-B1 | Polyfluorinated fluorenes and use thereof in liquid crystal mixtures | CLARIANT INT LTD (CH) | 2004-03-03 | — | — | EP | disclosed |
| EP-1223210-A1 | Polyfluorinated fluorenes and use thereof in liquid crystal mixtures | CLARIANT INTERNATIONAL LTD. (CH) | 2002-07-17 | — | — | EP | disclosed |