SCHEMBL6911378

SCHEMBL6911378

C=CCS(=O)(=O)c1ncccn1

nearest known ligand 0.53

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.53
KDM4E B2RXH2 1/20 0.53
MAPT P10636 2/20 0.41
MEN1 O00255 1/20 0.41
LMNA P02545 1/20 0.41
HTT P42858 1/20 0.41
KMT2A Q03164 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
PNMT P11086 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10980539 0.78 ALDH1A1 (0.38) ALDH1A1KDM4EMAPTMEN1LMNA
SCHEMBL10416944 0.76 KDM4E (0.51) ALDH1A1KDM4EMAPTMEN1LMNA
SCHEMBL22894765 0.76 ALDH1A1 (0.37) ALDH1A1KDM4EL3MBTL1
SCHEMBL9488733 0.76 ALDH1A1 (0.63) ALDH1A1KDM4EMAPTMEN1LMNA
SCHEMBL6260482 0.76 ALDH1A1 (0.44) ALDH1A1KDM4EMAPTMEN1LMNA
SCHEMBL11217679 0.75 ALDH1A1 (0.50) ALDH1A1KDM4EMAPTMEN1LMNA
SCHEMBL23442160 0.72 KDM4E (0.35) ALDH1A1KDM4E
SCHEMBL17542323 0.72 ALDH1A1 (0.38) ALDH1A1KDM4EMEN1KMT2A
SCHEMBL28796452 0.72 ALDH1A1 (0.63) ALDH1A1KDM4EMAPTMEN1LMNA
SCHEMBL23516919 0.72 KDM4E (0.35) ALDH1A1KDM4EKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6348471-B1 FUNGICIDES, AND ALSO TO NOVEL INTERMEDIATES AND TO A PROCESS FOR THEIR PREPARATION. BAYER AKTIENGESELLSCHAFT (DE) 2002-02-19 US claimed
US-6262051-B1 Fungicidal methoximinomethyldioxazines BAYER AKTIENGESELLSCHAFT (DE) 2001-07-17 US claimed
EP-1000037-A1 PYRIMIDYL OXYPHENYLACETIC ACID DERIVATIVES Bayer Aktiengesellschaft (DE) 2000-05-17 EP claimed
EP-0973770-A1 FUNGICIDAL METHOXIMINOMETHYLDIOXAZINES BAYER AG (DE) 2000-01-26 EP claimed
WO-1999005122-A1 PYRIMIDYL OXYPHENYLACETIC ACID DERIVATIVES BAYER AKTIENGESELLSCHAFT (DE) 1999-02-04 WO claimed
WO-1998045289-A1 FUNGICIDAL METHOXIMINOMETHYLDIOXAZINES BAYER AKTIENGESELLSCHAFT (DE) 1998-10-15 WO claimed
EP-0410590-B1 Pyrimidinyl herbicides AGREVO UK LTD (GB) 1994-06-22 EP claimed
US-4711959-A REACTING 2-ALKYLSULPHONYL-PYRIMIDINE WITH CYANAMIDE OR METAL SALT OF CYANAMIDE BAYER AKTIENGESELLSCHAFT (DE) 1987-12-08 US claimed
JP-3058976-A None JP disclosed
CN-114761384-A Process for the synthesis of 2-thioalkyl pyrimidines FMC公司 2022-07-15 CN disclosed
CN-114746406-A Method for synthesizing 2- (5-isoxazolyl) -phenol FMC公司 2022-07-12 CN disclosed
CN-107834117-B Secondary battery, battery pack, and vehicle 株式会社东芝 2020-12-29 CN disclosed
CN-105026376-B Process for the preparation of bispyribac-sodium and intermediates thereof 加尔达化学有限公司 2018-05-11 CN disclosed
WO-2014128719-A2 PROCESSES FOR THE PREPARATION OF BISPYRIBAC SODIUM AND INTERMEDIATES THEREOF GHARDA CHEMICALS LTD (IN) 2014-08-28 WO disclosed
US-4711959-A REACTING 2-ALKYLSULPHONYL-PYRIMIDINE WITH CYANAMIDE OR METAL SALT OF CYANAMIDE BAYER AKTIENGESELLSCHAFT (DE) 1987-12-08 US disclosed
US-4711959-A REACTING 2-ALKYLSULPHONYL-PYRIMIDINE WITH CYANAMIDE OR METAL SALT OF CYANAMIDE BAYER AKTIENGESELLSCHAFT (DE) 1987-12-08 US disclosed
EP-0024260-B1 PYRIMIDINE COMPOUNDS, THEIR PREPARATION, HERBICIDAL COMPOSITIONS CONTAINING THEM AS ACTIVE COMPOUNDS AND INTERMEDIATES THEREOF CIBA-GEIGY AG (CH) 1985-05-22 EP disclosed
US-4314812-A Two-phase printing process for preparing conversion articles and discharge resist prints HOECHST AKTIENGESELLSCHAFT (DE) 1982-02-09 US disclosed
US-4314811-A Two-phase printing process for preparing conversion articles and discharge resist prints HOECHST AKTIENGESELLSCHAFT (DE) 1982-02-09 US disclosed
EP-0024260-A2 Pyrimidine compounds, their preparation, herbicidal compositions containing them as active compounds and intermediates thereof CIBA-GEIGY AG (CH) 1981-02-25 EP disclosed