Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | CALM1 | P0DP23 | 2/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | BCR | P11274 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1162423 | 0.81 | ALDH1A1 (0.52) | ALDH1A1CYP1A1CYP1B1CYP19A1CALM1 | |
| SCHEMBL1514243 | 0.79 | ALDH1A1 (0.63) | ALDH1A1CYP1A1CYP1B1CYP19A1AKR1B1 | |
| SCHEMBL29003102 | 0.79 | ALDH1A1 (0.50) | ALDH1A1CYP1A1CYP1B1CYP19A1CALM1 | |
| SCHEMBL28597517 | 0.79 | ALDH1A1 (0.50) | ALDH1A1CYP1A1CYP1B1CYP19A1CALM1 | |
| SCHEMBL8049885 | 0.79 | ALDH1A1 (0.50) | ALDH1A1CYP1A1CYP1B1CYP19A1CALM1 | |
| SCHEMBL8345177 | 0.79 | ALDH1A1 (0.50) | ALDH1A1CYP1A1CYP1B1CYP19A1CALM1 | |
| SCHEMBL3503547 | 0.79 | TAAR1 (0.56) | — | |
| SCHEMBL3933929 | 0.76 | ALDH1A1 (0.65) | ALDH1A1CALM1TSHRTP53CYP3A4 | |
| SCHEMBL43447 | 0.75 | ALDH1A1 (0.58) | ALDH1A1CYP1A1CYP1B1CYP19A1CALM1 | |
| SCHEMBL5252553 | 0.74 | ALDH1A1 (0.65) | ALDH1A1CYP1A1CYP1B1CYP19A1CALM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3823810-A2 | RESIN COMPOSITION SUITABLE FOR PRINTING AND PRINTING METHODS | Montanuniversität Leoben (AT) | 2021-05-26 | — | — | EP | disclosed |
| US-20200063130-A1 | CHIMERIC RNA OLIGONUCLEOTIDES AND USES THEREOF | Università Cattolica del Sacro Cuore (IT) | 2020-02-27 | — | — | US | disclosed |
| WO-2020016343-A2 | RESIN COMPOSITION SUITABLE FOR PRINTING AND PRINTING METHODS | Montanuniversität Leoben (AT) | 2020-01-23 | — | — | WO | disclosed |
| US-20190345190-A1 | PHOSPHONATE ANALOGS OF HIV INHIBITOR COMPOUNDS | GILEAD SCIENCES, INC. | 2019-11-14 | — | — | US | disclosed |
| EP-3497446-A1 | METHOD AND COMPOSITION FOR DETECTION OF PEPTIDE CYCLIZATION USING PROTEIN TAGS | H. Hoffnabb-La Roche Ag (CH) | 2019-06-19 | — | — | EP | disclosed |
| EP-3286362-A1 | METHOD AND COMPOSITION FOR PEPTIDE CYCLIZATION AND PROTEASE TREATMENT | F. Hoffmann-La Roche AG (CH) | 2018-02-28 | — | — | EP | disclosed |
| WO-2018033478-A1 | METHOD AND COMPOSITION FOR DETECTION OF PEPTIDE CYCLIZATION USING PROTEIN TAGS | F. HOFFMANN-LA ROCHE AG (CH) | 2018-02-22 | — | — | WO | disclosed |
| EP-3140310-A1 | SYNTHESIS OF BORONATE SALTS AND USES THEREOF | Rempex Pharmaceuticals, Inc. (US) | 2017-03-15 | — | — | EP | disclosed |
| EP-3131952-A1 | RESIN COMPOSITION SUITABLE FOR PRINTING AND PRINTING METHOD UTILIZING THE SAME | Montanuniversität Leoben (AT) | 2017-02-22 | — | — | EP | disclosed |
| WO-2015171430-A1 | SYNTHESIS OF BORONATE SALTS AND USES THEREOF | REMPEX PHARMACEUTICALS, INC. (US) | 2015-11-12 | — | — | WO | disclosed |
| WO-1999010365-A2 | 5',5'-LINKED OLIGOMERS HAVING ANTI-THROMBIN ACTIVITY | GILEAD SCIENCES, INC. (US) | 1999-03-04 | — | — | WO | disclosed |
| WO-1998017647-A1 | PIPERIDINE COMPOUNDS | GILEAD SCIENCES, INC. (US) | 1998-04-30 | — | — | WO | disclosed |
| WO-1998007685-A1 | PREPARATION OF CYCLOHEXENE CARBOXYLATE DERIVATIVES | GILEAD SCIENCES, INC. (US) | 1998-02-26 | — | — | WO | disclosed |
| EP-0821690-A1 | NOVEL COMPOUNDS AND METHODS FOR THERAPY | Ustav Organicke Chemie A Biochemie Akademie Ved Ceske Republiky (CZ) | 1998-02-04 | — | — | EP | disclosed |
| WO-1997049723-A1 | CATIONIC LIPIDS FOR DELIVERY OF NUCLEIC ACID TO CELLS | GILEAD SCIENCES, INC. (US) | 1997-12-31 | — | — | WO | disclosed |
| EP-0807118-A2 | NOVEL COMPOUNDS AND METHODS FOR MAKING AND USING SAME | GILEAD SCIENCES, INC. (US) | 1997-11-19 | — | — | EP | disclosed |
| EP-0789695-A2 | THIEPANE COMPOUNDS INHIBITING AND DETECTING HIV PROTEASE | GILEAD SCIENCES, INC. (US) | 1997-08-20 | — | — | EP | disclosed |
| EP-0759917-A1 | NOVEL SELECTIVE INHIBITORS OF VIRAL OR BACTERIAL NEURAMINIDASES | GILEAD SCIENCES, INC. (US) | 1997-03-05 | — | — | EP | disclosed |
| WO-1996026933-A9 | NOVEL SELECTIVE INHIBITORS OF VIRAL OR BACTERIAL NEURAMINIDASES | — | 1996-11-28 | — | — | WO | disclosed |
| WO-1996023801-A2 | NOVEL COMPOUNDS AND METHODS FOR MAKING AND USING SAME | GILEAD SCIENCES, INC. (US) | 1996-08-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190345190-A1 | PHOSPHONATE ANALOGS OF HIV INHIBITOR COMPOUNDS | PIK3CA, TYMP, ITPA | ALDH1A1 4577/4885CYP1A1 4752/4885CYP1B1 4560/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.