Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8608029 | 0.97 | — | — | |
| SCHEMBL8609553 | 0.96 | — | — | |
| Hydrochloric Acid SCHEMBL6726901 | 0.81 | — | — | |
| SCHEMBL7094146 | 0.81 | — | — | |
| SCHEMBL4652069 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL8609693 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL6064957 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL6912225 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL8167502 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL6295594 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0810234-B1 | Method for making and using a supported metallocene catalyst system | PHILLIPS PETROLEUM CO (US) | 2000-02-16 | — | — | EP | claimed |
| EP-0685495-B1 | Method for using a supported metallocene catalyst system | PHILLIPS PETROLEUM CO (US) | 1998-04-08 | — | — | EP | claimed |
| US-6730758-B2 | ADDITION POLYMERIZATION OF ALPHA-OLEFIN HYDROCARBON IN PRESENCE OF SELF-SUPPORTED VINYLOLEFIN-PREPOLYMERIZED CATALYST | ALBEMARLE CORPORATION | 2004-05-04 | — | — | US | disclosed |
| US-20030191254-A1 | PARTICULATE GROUP 4 METALLOCENE-ALUMINOXANE CATALYST COMPOSITIONS DEVOID OF PREFORMED SUPPORT, AND THEIR PREPARATION AND THEIR USE | ALBEMARLE CORPORATION | 2003-10-09 | — | — | US | disclosed |
| US-6551955-B1 | Olefin polymerization catalysts; efficiency | ALBEMARLE CORPORATION | 2003-04-22 | — | — | US | disclosed |
| US-6268453-B1 | ORGANOALUMINUM CATALYSTS WITH DILUENTS FOR POLYMERIZATION OF OLEFINS | PHILLIPS PETROLEUM COMPANY | 2001-07-31 | — | — | US | disclosed |
| US-6153716-A | NARROW MOLECULAR WEIGHT DISTRIBUTION | PHILLIPS PETROLEUM COMPANY (US) | 2000-11-28 | — | — | US | disclosed |
| EP-1037931-A1 | CATALYST COMPOSITIONS OF ENHANCED PRODUCTIVITY | ALBEMARLE CORPORATION (US) | 2000-09-27 | — | — | EP | disclosed |
| US-5990035-A | PREPARING A SOLID COCATALYST BY CONTACTING AN ORGANOALUMINUM COMPOUND WITH A FIRST MATERIAL SUCH AS STARCH, CELLULOSE, SILICA, ALUMINUM TRIFLUORIDE, BORON OXIDE, AND 1,5-HEXANEDIOL THEN PASSING WATER DISPERSED IN INERT GAS TO FORM A SOLID | PHILLIPS PETROLEUM COMPANY, A DELAWARE CORPORATION | 1999-11-23 | — | — | US | disclosed |
| WO-1999029738-A1 | CATALYST COMPOSITIONS OF ENHANCED PRODUCTIVITY | ALBEMARLE CORPORATION (US) | 1999-06-17 | — | — | WO | disclosed |