Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 2/20 | 0.43 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | CDC25A | P30304 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrahydrofuran SCHEMBL11352874 | 1.00 | HTT (0.52) | HTTTHRBMEN1KMT2AMAPT | |
| Tetrahydrofuran SCHEMBL10631206 | 1.00 | HTT (0.52) | HTTTHRBMEN1KMT2AMAPT | |
| Tetrahydrofuran SCHEMBL8587992 | 0.98 | HTT (0.48) | HTTTHRBMEN1KMT2AMAPT | |
| Tetrahydrofuran SCHEMBL1322236 | 0.93 | TSHR (0.48) | HTTTHRBMEN1KMT2AMAPT | |
| SCHEMBL6819723 | 0.91 | TSHR (0.46) | HTTTHRBMEN1KMT2AMAPT | |
| SCHEMBL1046428 | 0.91 | TSHR (0.46) | HTTTHRBMEN1KMT2AMAPT | |
| Oxirane SCHEMBL25438415 | 0.90 | THRB (0.56) | HTTTHRBMEN1KMT2AMAPT | |
| Oxirane SCHEMBL7973667 | 0.90 | THRB (0.56) | HTTTHRBMEN1KMT2AMAPT | |
| Oxirane SCHEMBL3423801 | 0.90 | THRB (0.56) | HTTTHRBMEN1KMT2AMAPT | |
| Oxirane SCHEMBL3419644 | 0.90 | THRB (0.56) | HTTTHRBMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0878484-B1 | A process for the preparation of a megnesium halide supported metallocene catalyst | COUNCIL SCIENT IND RES (IN) | 2004-12-15 | — | — | EP | disclosed |