SCHEMBL691196

SCHEMBL691196

C[Zr](C)(=[SiH2])(C1C(CC2CCCC2)=Cc2c(-c3ccccc3)ccc(-c3ccccc3)c21)C1C(CC2CCCC2)=Cc2c(-c3ccccc3)ccc(-c3ccccc3)c21

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.32
RAB9A P51151 1/20 0.32
HTT P42858 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL690130 0.99 ALDH1A1 (0.32) ALDH1A1RAB9AHTTNPSR1
SCHEMBL690892 0.99 ALDH1A1 (0.34) ALDH1A1RAB9AHTTNPSR1MEN1
SCHEMBL691029 0.99 ALDH1A1 (0.34) ALDH1A1RAB9AHTTNPSR1MEN1
Hydrochloric Acid SCHEMBL690836 0.98 ALDH1A1 (0.33) ALDH1A1RAB9AMEN1KMT2ATDP1
Hydrochloric Acid SCHEMBL690532 0.98 ALDH1A1 (0.33) ALDH1A1RAB9AMEN1KMT2ATDP1
SCHEMBL691244 0.98
Hydrochloric Acid SCHEMBL688970 0.96
SCHEMBL691216 0.95
Hydrochloric Acid SCHEMBL689870 0.94
SCHEMBL690551 0.89

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2203486-B9 RACEMOSELECTIVE SYNTHESIS OF ANSA-METALLOCENE COMPOUNDS, ANSA-METALLOCENE COMPOUNDS, CATALYSTS COMPRISING THEM, PROCESS FOR PRODUCING AN OLEFIN POLYMER BY USE OF THE CATALYSTS, AND OLEFIN HOMO- AND COPOLYMERS LUMMUS NOVOLEN TECHNOLOGY GMBH (DE) 2012-08-01 EP claimed
EP-2203486-B1 RACEMOSELECTIVE SYNTHESIS OF ANSA-METALLOCENE COMPOUNDS, ANSA-METALLOCENE COMPOUNDS, CATALYSTS COMPRISING THEM, PROCESS FOR PRODUCING AN OLEFIN POLYMER BY USE OF THE CATALYSTS, AND OLEFIN HOMO- AND COPOLYMERS LUMMUS NOVOLEN TECHNOLOGY GMBH (DE) 2012-02-29 EP claimed