SCHEMBL6912083

SCHEMBL6912083

CCN(CC)C(=O)c1ccc(C(=O)OC)cc1S(=O)(=O)NC(=O)Nc1nc(C)cc(OC)n1

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CDK1 P06493 1/20 0.52
GAA P10253 2/20 0.44
TSHR P16473 3/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
KDM4E B2RXH2 4/20 0.39
ALDH1A1 P00352 2/20 0.39
GLA P06280 2/20 0.39
CYP1A2 P05177 1/20 0.37
CYP2C19 P33261 1/20 0.37
LMNA P02545 1/20 0.36
POLB P06746 1/20 0.36
MEN1 O00255 1/20 0.36
HPGD P15428 1/20 0.36
KMT2A Q03164 1/20 0.36
RXFP1 Q9HBX9 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7062494 0.90 CDK1 (0.64) CDK1GAATSHRSMN1; SMN2KDM4E
SCHEMBL6905978 0.87 CDK1 (0.58) CDK1GAATSHRSMN1; SMN2ALDH1A1
SCHEMBL7060712 0.85 CDK1 (0.73) CDK1GAATSHRSMN1; SMN2KDM4E
SCHEMBL11385667 0.83 CDK1 (0.57) CDK1GAASMN1; SMN2KDM4EALDH1A1
SCHEMBL11375418 0.81 KDM4E (0.48) CDK1GAASMN1; SMN2KDM4EALDH1A1
SCHEMBL11378542 0.81 CDK1 (0.52) CDK1GAATSHRSMN1; SMN2KDM4E
SCHEMBL6912806 0.81 CDK1 (0.64) CDK1GAAKDM4EALDH1A1GLA
SCHEMBL6911957 0.81 CDK1 (0.64) CDK1GAASMN1; SMN2ALDH1A1GLA
SCHEMBL6913737 0.80 CDK1 (0.61) CDK1GAASMN1; SMN2ALDH1A1GLA
SCHEMBL6906777 0.80 CDK1 (0.63) CDK1GAAGLACYP1A2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1104239-B1 HERBICIDES WITH ACYLATED AMINOPHENYLSULFONYL UREA BAYER CROPSCIENCE GMBH (DE) 2004-02-18 EP disclosed
EP-1231839-B1 HERBICIDE MEANS WITH ACYLATED AMINO PHENYL SULFONYL CARBAMIDE BAYER CROPSCIENCE GMBH (DE) 2003-05-14 EP disclosed
US-6498126-B1 Herbicide combination with acylated aminophenylsulfonylureas AVENTIS CROPSCIENCE GMBH (DE) 2002-12-24 US disclosed
EP-1231839-A2 HERBICIDE MEANS WITH ACYLATED AMINO PHENYL SULFONYL CARBAMIDE Aventis CropScience GmbH (DE) 2002-08-21 EP disclosed
EP-1104239-A1 HERBICIDES WITH ACYLATED AMINOPHENYLSULFONYL UREA Aventis CropScience GmbH (DE) 2001-06-06 EP disclosed
WO-2001035742-A2 HERBICIDE MEANS WITH ACYLATED AMINO PHENYL SULFONYL CARBAMIDE AVENTIS CROPSCIENCE GMBH (DE) 2001-05-25 WO disclosed
WO-2000008932-A1 HERBICIDES WITH ACYLATED AMINOPHENYLSULFONYL UREA AVENTIS CROPSCIENCE GMBH (DE) 2000-02-24 WO disclosed