SCHEMBL6913737

SCHEMBL6913737

CCOC(=O)Nc1ccc(C(=O)N(CC)CC)c(S(=O)(=O)NC(=O)Nc2nc(OC)cc(OC)n2)c1

nearest known ligand 0.61

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CDK1 P06493 1/20 0.61
GAA P10253 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.39
ALDH1A1 P00352 3/20 0.38
USP2 O75604 1/20 0.38
KCNQ2 O43526 1/20 0.37
TP53 P04637 1/20 0.36
GLA P06280 1/20 0.36
MAPT P10636 1/20 0.36
KMT2A Q03164 1/20 0.36
HCRTR1 O43613 1/20 0.36
HCRTR2 O43614 1/20 0.36
LMNA P02545 1/20 0.36
RECQL P46063 1/20 0.36
HSD17B10 Q99714 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6912806 0.94 CDK1 (0.64) CDK1GAAALDH1A1USP2TP53
SCHEMBL6912875 0.92 CDK1 (0.73) CDK1GAASMN1; SMN2ALDH1A1USP2
SCHEMBL6911957 0.90 CDK1 (0.64) CDK1GAASMN1; SMN2ALDH1A1TP53
SCHEMBL6906777 0.89 CDK1 (0.63) CDK1GAATP53GLAMAPT
SCHEMBL6913207 0.88 CDK1 (0.61) CDK1GAAALDH1A1TP53GLA
SCHEMBL6905978 0.87 CDK1 (0.58) CDK1GAASMN1; SMN2ALDH1A1
SCHEMBL6905160 0.86 CDK1 (0.81) CDK1GAAALDH1A1USP2TP53
SCHEMBL7060712 0.83 CDK1 (0.73) CDK1GAASMN1; SMN2ALDH1A1MAPT
SCHEMBL2977298 0.83 CDK1 (0.79) CDK1GAASMN1; SMN2USP2TP53
SCHEMBL5847836 0.82 CDK1 (0.78) CDK1GAAALDH1A1USP2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1104239-B1 HERBICIDES WITH ACYLATED AMINOPHENYLSULFONYL UREA BAYER CROPSCIENCE GMBH (DE) 2004-02-18 EP disclosed
EP-1231839-B1 HERBICIDE MEANS WITH ACYLATED AMINO PHENYL SULFONYL CARBAMIDE BAYER CROPSCIENCE GMBH (DE) 2003-05-14 EP disclosed
US-6498126-B1 Herbicide combination with acylated aminophenylsulfonylureas AVENTIS CROPSCIENCE GMBH (DE) 2002-12-24 US disclosed
EP-1231839-A2 HERBICIDE MEANS WITH ACYLATED AMINO PHENYL SULFONYL CARBAMIDE Aventis CropScience GmbH (DE) 2002-08-21 EP disclosed
EP-1104239-A1 HERBICIDES WITH ACYLATED AMINOPHENYLSULFONYL UREA Aventis CropScience GmbH (DE) 2001-06-06 EP disclosed
WO-2001035742-A2 HERBICIDE MEANS WITH ACYLATED AMINO PHENYL SULFONYL CARBAMIDE AVENTIS CROPSCIENCE GMBH (DE) 2001-05-25 WO disclosed
WO-2000008932-A1 HERBICIDES WITH ACYLATED AMINOPHENYLSULFONYL UREA AVENTIS CROPSCIENCE GMBH (DE) 2000-02-24 WO disclosed