Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.67 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.63 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | TP53 | P04637 | 4/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 5/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | CNR2 | P34972 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | ESR1 | P03372 | 1/20 | 0.60 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 4/20 | 0.59 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6439028 | 0.95 | ESR1 (0.67) | ALDH1A1RPS6KB1ROCK1NPSR1RAB9A | |
| SCHEMBL30746859 | 0.95 | ESR1 (0.67) | ALDH1A1RPS6KB1ROCK1NPSR1RAB9A | |
| SCHEMBL8025747 | 0.95 | ALDH1A1 (0.65) | ALDH1A1RPS6KB1ROCK1NPSR1RAB9A | |
| SCHEMBL28161177 | 0.93 | ALDH1A1 (0.60) | ALDH1A1RPS6KB1ROCK1NPSR1RAB9A | |
| SCHEMBL8011388 | 0.93 | TP53 (0.66) | ALDH1A1RPS6KB1ROCK1NPSR1RAB9A | |
| SCHEMBL6439069 | 0.90 | ALDH1A1 (0.56) | ALDH1A1RPS6KB1ROCK1NPSR1RAB9A | |
| SCHEMBL6439260 | 0.89 | CNR2 (0.63) | ALDH1A1RPS6KB1ROCK1NPSR1RAB9A | |
| SCHEMBL6441068 | 0.88 | CNR2 (0.62) | ALDH1A1RPS6KB1ROCK1NPSR1RAB9A | |
| SCHEMBL6440399 | 0.85 | RPS6KB1 (0.58) | ALDH1A1RPS6KB1ROCK1NPSR1RAB9A | |
| SCHEMBL6439151 | 0.85 | RPS6KB1 (0.55) | ALDH1A1RPS6KB1ROCK1NPSR1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040002524-A1 | Benzimidazole compounds and their use as estrogen agonists/antagonists | CHESWORTH RICHARD (US) | 2004-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040002524-A1 | Benzimidazole compounds and their use as estrogen agonists/antagonists | ESR1, GPER1, ESR2 | ALDH1A1 581/4885RPS6KB1 3429/4885ROCK1 3937/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.