Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.34 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.33 |
| ▸ | GABRE | P78334 | 1/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.33 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.33 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.33 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6912504 | 0.82 | HTT (0.37) | — | |
| SCHEMBL6909445 | 0.78 | TLR8 (0.33) | TLR8GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL9132401 | 0.77 | — | — | |
| SCHEMBL9578834 | 0.74 | — | — | |
| SCHEMBL6914527 | 0.74 | SKP2 (0.39) | TLR8SKP2NOS2 | |
| SCHEMBL27783781 | 0.71 | ALDH1A1 (0.33) | SKP2NOS2 | |
| SCHEMBL31510796 | 0.71 | ALDH1A1 (0.33) | SKP2NOS2 | |
| SCHEMBL28902346 | 0.70 | ALDH1A1 (0.31) | TLR8 | |
| SCHEMBL8764640 | 0.70 | BCL2 (0.38) | — | |
| SCHEMBL19988191 | 0.69 | HTT (0.42) | NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1265940-B1 | AROMATIC AMINE CURATIVES AND THEIR USE | ALBERMARLE CORP (US) | 2004-10-27 | — | — | EP | disclosed |
| US-6509434-B1 | Condensation polymerization of alkylthiated mononuclear aromatic amines and isocyanate prepolymer to produce polyurethanes, polyureaurethanes and/or polyureas | ALBEMARLE CORPORATION | 2003-01-21 | — | — | US | disclosed |
| EP-1265940-A2 | AROMATIC AMINE CURATIVES AND THEIR USE | Albermarle Corporation (US) | 2002-12-18 | — | — | EP | disclosed |
| WO-2001070841-A2 | AROMATIC AMINE CURATIVES AND THEIR USE | ALBEMARLE CORPORATION (US) | 2001-09-27 | — | — | WO | disclosed |