SCHEMBL6912875

SCHEMBL6912875

CCOC(=O)Nc1ccc(C(=O)N(C)C)c(S(=O)(=O)NC(=O)Nc2nc(OC)cc(OC)n2)c1

nearest known ligand 0.73

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CDK1 P06493 1/20 0.73
GAA P10253 1/20 0.47
SMN1; SMN2 Q16637 2/20 0.39
USP2 O75604 1/20 0.38
ALDH1A1 P00352 4/20 0.38
HPGD P15428 1/20 0.38
MTNR1A P48039 1/20 0.37
MTNR1B P49286 1/20 0.37
TP53 P04637 1/20 0.37
GLA P06280 1/20 0.37
MAPT P10636 1/20 0.37
KMT2A Q03164 1/20 0.37
LMNA P02545 1/20 0.36
RECQL P46063 1/20 0.36
HSD17B10 Q99714 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6913737 0.92 CDK1 (0.61) CDK1GAASMN1; SMN2USP2ALDH1A1
SCHEMBL2977298 0.92 CDK1 (0.79) CDK1GAASMN1; SMN2USP2TP53
SCHEMBL5847836 0.91 CDK1 (0.78) CDK1GAAUSP2ALDH1A1TP53
SCHEMBL5847825 0.91 CDK1 (0.78) CDK1GAASMN1; SMN2USP2TP53
SCHEMBL28551087 0.90 CDK1 (0.79) CDK1GAASMN1; SMN2USP2TP53
SCHEMBL6105235 0.90 CDK1 (0.82) CDK1GAASMN1; SMN2USP2TP53
SCHEMBL6107089 0.89 CDK1 (0.75) CDK1GAAMTNR1AMTNR1BTP53
SCHEMBL2979898 0.88 CDK1 (0.74) CDK1GAAMTNR1AMTNR1BTP53
SCHEMBL2979899 0.88 CDK1 (0.74) CDK1GAAUSP2MTNR1AMTNR1B
SCHEMBL6106106 0.88 CDK1 (0.79) CDK1GAASMN1; SMN2USP2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1104239-B1 HERBICIDES WITH ACYLATED AMINOPHENYLSULFONYL UREA BAYER CROPSCIENCE GMBH (DE) 2004-02-18 EP disclosed
EP-1231839-B1 HERBICIDE MEANS WITH ACYLATED AMINO PHENYL SULFONYL CARBAMIDE BAYER CROPSCIENCE GMBH (DE) 2003-05-14 EP disclosed
US-6498126-B1 Herbicide combination with acylated aminophenylsulfonylureas AVENTIS CROPSCIENCE GMBH (DE) 2002-12-24 US disclosed
EP-1104239-A1 HERBICIDES WITH ACYLATED AMINOPHENYLSULFONYL UREA Aventis CropScience GmbH (DE) 2001-06-06 EP disclosed
WO-2000008932-A1 HERBICIDES WITH ACYLATED AMINOPHENYLSULFONYL UREA AVENTIS CROPSCIENCE GMBH (DE) 2000-02-24 WO disclosed