Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8157593 | 0.66 | — | — | |
| Hydrochloric Acid SCHEMBL6309977 | 0.61 | — | — | |
| Hydrochloric Acid SCHEMBL29236921 | 0.58 | EPHX2 (0.31) | — | |
| Hydrochloric Acid SCHEMBL30117035 | 0.57 | — | — | |
| Hydrochloric Acid SCHEMBL9169562 | 0.57 | — | — | |
| Hydrochloric Acid SCHEMBL29105442 | 0.57 | — | — | |
| Hydrochloric Acid SCHEMBL29779668 | 0.57 | — | — | |
| SCHEMBL3671173 | 0.57 | — | — | |
| Hydrochloric Acid SCHEMBL29281375 | 0.56 | — | — | |
| Hydrochloric Acid SCHEMBL7100658 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1141046-B1 | SLURRY POLYMERIZATION PROCESS USING AN UNSUPPORTED PHOSPHINIMINE CATALYST | NOVA CHEM INT SA (CH) | 2004-03-03 | — | — | EP | disclosed |
| EP-1141046-A1 | SLURRY POLYMERIZATION PROCESS USING AN UNSUPPORTED PHOSPHINIMINE CATALYST | Nova Chemicals (International) S.A. (CH) | 2001-10-10 | — | — | EP | disclosed |
| US-6235853-B1 | Slurry polymerization process using an unsupported phosphinimine catalyst | NOVA CHEMICALS (INTERNATIONAL) S.A. | 2001-05-22 | — | — | US | disclosed |
| WO-2000031155-A1 | SLURRY POLYMERIZATION PROCESS USING AN UNSUPPORTED PHOSPHINIMINE CATALYST | NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) | 2000-06-02 | — | — | WO | disclosed |