SCHEMBL6913207

SCHEMBL6913207

CCN(CC)C(=O)c1ccc(NC(=O)C(C)C)cc1S(=O)(=O)NC(=O)Nc1nc(OC)cc(OC)n1

nearest known ligand 0.61

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CDK1 P06493 1/20 0.61
GAA P10253 1/20 0.46
KCNB1 Q14721 2/20 0.38
KCNA5 P22460 1/20 0.38
TP53 P04637 1/20 0.36
GLA P06280 1/20 0.36
MAPT P10636 1/20 0.36
CYP1A2 P05177 1/20 0.35
ALDH1A1 P00352 1/20 0.35
HCRTR1 O43613 1/20 0.34
HCRTR2 O43614 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6910101 0.90 CDK1 (0.75) CDK1GAAKCNB1KCNA5TP53
SCHEMBL6911957 0.90 CDK1 (0.64) CDK1GAATP53GLAMAPT
SCHEMBL6912806 0.90 CDK1 (0.64) CDK1GAATP53GLAMAPT
SCHEMBL6906777 0.89 CDK1 (0.63) CDK1GAATP53GLAMAPT
SCHEMBL27542669 0.88 CDK1 (0.47) CDK1GAAKCNB1KCNA5
SCHEMBL6913737 0.88 CDK1 (0.61) CDK1GAATP53GLAMAPT
SCHEMBL6905160 0.86 CDK1 (0.81) CDK1GAATP53GLAMAPT
SCHEMBL6905978 0.85 CDK1 (0.58) CDK1GAACYP1A2ALDH1A1
SCHEMBL7060712 0.82 CDK1 (0.73) CDK1GAAMAPTALDH1A1
SCHEMBL6105235 0.81 CDK1 (0.82) CDK1GAATP53GLAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1104239-B1 HERBICIDES WITH ACYLATED AMINOPHENYLSULFONYL UREA BAYER CROPSCIENCE GMBH (DE) 2004-02-18 EP disclosed
EP-1231839-B1 HERBICIDE MEANS WITH ACYLATED AMINO PHENYL SULFONYL CARBAMIDE BAYER CROPSCIENCE GMBH (DE) 2003-05-14 EP disclosed
US-6498126-B1 Herbicide combination with acylated aminophenylsulfonylureas AVENTIS CROPSCIENCE GMBH (DE) 2002-12-24 US disclosed
EP-1231839-A2 HERBICIDE MEANS WITH ACYLATED AMINO PHENYL SULFONYL CARBAMIDE Aventis CropScience GmbH (DE) 2002-08-21 EP disclosed
US-6372919-B1 SUBSTANTIALLY FREE OF CORRESPONDING (-)-ENANTIOMER DOV PHARMACEUTICAL, INC. 2002-04-16 US disclosed
EP-1104239-A1 HERBICIDES WITH ACYLATED AMINOPHENYLSULFONYL UREA Aventis CropScience GmbH (DE) 2001-06-06 EP disclosed
WO-2001035742-A2 HERBICIDE MEANS WITH ACYLATED AMINO PHENYL SULFONYL CARBAMIDE AVENTIS CROPSCIENCE GMBH (DE) 2001-05-25 WO disclosed
WO-2000008932-A1 HERBICIDES WITH ACYLATED AMINOPHENYLSULFONYL UREA AVENTIS CROPSCIENCE GMBH (DE) 2000-02-24 WO disclosed