SCHEMBL6914014

SCHEMBL6914014

C1=CCC([Zr](C2=CC=CC2)C(c2ccccc2)c2ccccc2)=C1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CRHBP P24387 1/20 0.33
CRHR2 Q13324 1/20 0.33
CYP2D6 P10635 2/20 0.32
CHRM2 P08172 1/20 0.32
CHRM4 P08173 1/20 0.32
CHRM5 P08912 1/20 0.32
ADRA2A P08913 1/20 0.32
ADORA3 P0DMS8 1/20 0.32
CHRM1 P11229 1/20 0.32
CHRM3 P20309 1/20 0.32
DRD1 P21728 1/20 0.32
ADRA1D P25100 1/20 0.32
HTR2A P28223 1/20 0.32
HTR2C P28335 1/20 0.32
HRH1 P35367 1/20 0.32
OPRM1 P35372 1/20 0.32
DRD3 P35462 1/20 0.32
HTR2B P41595 1/20 0.32
SLC6A3 Q01959 1/20 0.32
KCNH2 Q12809 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6917361 0.98 CRHBP (0.32) CRHBPCRHR2CYP2D6CHRM2CHRM4
SCHEMBL6024282 0.79 CRHBP (0.30) CRHBPCRHR2
SCHEMBL5615288 0.73 MEN1 (0.36)
Hydrochloric Acid SCHEMBL7933384 0.70 TAAR1 (0.40)
SCHEMBL7636795 0.69
SCHEMBL6907633 0.69
Hydrochloric Acid SCHEMBL3680370 0.69
SCHEMBL8041061 0.68
Hydrochloric Acid SCHEMBL6942846 0.68
Chloromethane SCHEMBL3680549 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115260366-A Catalyst system for forming multi-block copolymers 陶氏环球技术有限责任公司 2022-11-01 CN disclosed
CN-110603274-B Catalyst system for forming multi-block copolymers 陶氏环球技术有限责任公司 2022-09-30 CN disclosed
CN-110582518-B Catalyst system for forming multi-block copolymers 陶氏环球技术有限责任公司 2022-08-09 CN disclosed
CN-108541256-B Short-chain polyethylene homopolymers with improved grindability 科莱恩国际有限公司 2021-07-16 CN disclosed
CN-110603271-A Catalyst system for forming multi-block copolymers 陶氏环球技术有限责任公司 2019-12-20 CN disclosed
CN-110603274-A Catalyst system for forming multi-block copolymers 陶氏环球技术有限责任公司 2019-12-20 CN disclosed
CN-110582518-A Catalyst system for forming multi-block copolymers 陶氏环球技术有限责任公司 2019-12-17 CN disclosed
EP-0927201-B1 CATALYST SYSTEM FOR (CO)POLYMERIZATION OF OLEFINS AND PROCESS FOR THE PREPARATION OF OLEFIN (CO)POLYMERS USING THE CATALYST SYSTEM HYUNDAI PETROCHEMICAL CO LTD (KR) 2004-04-14 EP disclosed