SCHEMBL69141

SCHEMBL69141

Oc1ccc(Br)c(O)c1Cl

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.46
MAPK1 P28482 1/20 0.46
AR P10275 1/20 0.44
TSHR P16473 5/20 0.39
ALOX15 P16050 2/20 0.39
PIM1 P11309 1/20 0.35
NQO2 P16083 1/20 0.34
HSD17B10 Q99714 3/20 0.33
HPGD P15428 4/20 0.32
ALDH1A1 P00352 4/20 0.32
MEN1 O00255 3/20 0.32
MAPT P10636 3/20 0.32
KMT2A Q03164 3/20 0.32
TDP1 Q9NUW8 2/20 0.32
ALOX12 P18054 1/20 0.32
KDM4E B2RXH2 1/20 0.32
APEX1 P27695 1/20 0.32
RECQL P46063 1/20 0.32
BLM P54132 1/20 0.32
CASP1 P29466 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3747905 0.81 CYP3A4 (0.55) CYP3A4MAPK1ARTSHRALOX15
SCHEMBL28509016 0.79 CYP3A4 (0.46) CYP3A4MAPK1ARTSHRALOX15
SCHEMBL16815458 0.79 CYP3A4 (0.46) CYP3A4MAPK1ARTSHRHSD17B10
SCHEMBL6182858 0.77 MAPK1 (0.55) CYP3A4MAPK1TSHRALOX15PIM1
SCHEMBL18893999 0.75 DAO (0.34) ARHPGDALDH1A1MEN1MAPT
SCHEMBL20137111 0.75 CYP3A4 (0.37) CYP3A4ARALOX15HPGDALDH1A1
SCHEMBL16815430 0.75 CYP3A4 (0.42) CYP3A4MAPK1ARTSHRALOX15
SCHEMBL28796789 0.75 CYP3A4 (0.42) CYP3A4MAPK1ARTSHRALOX15
SCHEMBL37621 0.75 ALOX15 (0.43) CYP3A4ARTSHRALOX15PIM1
SCHEMBL286423 0.73 CYP3A4 (0.41) CYP3A4MAPK1ARTSHRALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed
WO-2004073612-A2 ESTROGEN RECEPTOR MODULATORS MERCK & CO. INC. (US) 2004-09-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 CYP3A4 2028/4885MAPK1 3382/4885AR 68/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.