Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.35 |
| ▸ | PPARG | P37231 | 6/20 | 0.35 |
| ▸ | PPARD | Q03181 | 6/20 | 0.35 |
| ▸ | PPARA | Q07869 | 6/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.35 |
| ▸ | TLR2 | O60603 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | FABP4 | P15090 | 2/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL554213 | 0.94 | TSHR (0.48) | TSHRKDM4EAPEX1CES1CES2 | |
| SCHEMBL147034 | 0.94 | TSHR (0.48) | TSHRKDM4EAPEX1CES1CES2 | |
| SCHEMBL147035 | 0.94 | TSHR (0.48) | TSHRKDM4EAPEX1CES1CES2 | |
| Water SCHEMBL28135417 | 0.92 | TSHR (0.46) | TSHRKDM4EAPEX1CES1CES2 | |
| Butane SCHEMBL6913001 | 0.92 | TSHR (0.46) | TSHRKDM4EAPEX1CES1CES2 | |
| Maleic Acid SCHEMBL31031690 | 0.88 | HCAR2 (0.44) | TSHRKDM4EAPEX1CES1CES2 | |
| SCHEMBL468339 | 0.88 | AKR1B1 (0.50) | TSHRKDM4EAPEX1CES1CES2 | |
| SCHEMBL3628619 | 0.88 | AKR1B1 (0.50) | TSHRKDM4EAPEX1CES1CES2 | |
| SCHEMBL555159 | 0.88 | AKR1B1 (0.50) | TSHRKDM4EAPEX1CES1CES2 | |
| SCHEMBL27969469 | 0.87 | TSHR (0.39) | TSHRKDM4EAPEX1CES1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040171867-A1 | Reactive monomer composition modified by a small-amount of lactones, an acrylic polyol resin, a curable resin composition, and a coating composition | OKAZAKI AKIRA (JP) | 2004-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040171867-A1 | Reactive monomer composition modified by a small-amount of lactones, an acrylic polyol resin, a curable resin composition, and a coating composition | MSR1, FUT4, MRE11 | TSHR 1750/4885KDM4E 577/4885APEX1 324/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.