SCHEMBL3628619

SCHEMBL3628619

CCCCC/C(=C/C(=O)O)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 1/20 0.50
GPR84 Q9NQS5 7/20 0.48
PPARG P37231 7/20 0.48
PPARD Q03181 7/20 0.48
PPARA Q07869 7/20 0.48
HDAC11 Q96DB2 5/20 0.48
TSHR P16473 5/20 0.48
PTPN1 P18031 3/20 0.48
ALDH1A1 P00352 2/20 0.48
TLR2 O60603 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
FABP4 P15090 2/20 0.48
ALOX15 P16050 2/20 0.48
HSD17B10 Q99714 2/20 0.48
SLC22A6 Q4U2R8 1/20 0.48
SLC22A8 Q8TCC7 1/20 0.48
MEN1 O00255 1/20 0.48
ESR1 P03372 1/20 0.48
PDE4A P27815 1/20 0.48
KMT2A Q03164 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL555159 1.00 AKR1B1 (0.50) AKR1B1GPR84PPARGPPARDPPARA
SCHEMBL468339 1.00 AKR1B1 (0.50) AKR1B1GPR84PPARGPPARDPPARA
SCHEMBL11537088 0.98 GPR84 (0.52) AKR1B1GPR84PPARGPPARDPPARA
SCHEMBL5516515 0.98 GPR84 (0.52) AKR1B1GPR84PPARGPPARDPPARA
SCHEMBL571487 0.98 GPR84 (0.52) AKR1B1GPR84PPARGPPARDPPARA
SCHEMBL891122 0.98 GPR84 (0.52) AKR1B1GPR84PPARGPPARDPPARA
SCHEMBL3629983 0.98 GPR84 (0.52) AKR1B1GPR84PPARGPPARDPPARA
SCHEMBL11072779 0.98 GPR84 (0.52) AKR1B1GPR84PPARGPPARDPPARA
SCHEMBL877868 0.98 GPR84 (0.52) AKR1B1GPR84PPARGPPARDPPARA
SCHEMBL7149850 0.98 GPR84 (0.52) AKR1B1GPR84PPARGPPARDPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0589430-B1 Water-absorptive contact lens MENICON CO LTD (JP) 1999-06-16 EP claimed
EP-0299025-B1 IMPROVED HAIR TREATING RESINS ISP INVESTMENTS INC. (US) 1993-05-19 EP claimed
CN-105467784-B Toner 佳能株式会社 2019-11-26 CN disclosed
CN-104583250-B Propylene oxide acids polymerizable composition for optical material and the preparation method of propylene oxide acids optical material that storage stability is improved 可奥熙搜路司有限公司 2017-07-07 CN disclosed
CN-104583250-A Polymerization composition for epoxy acrylic optical material having enhanced storage stability and method for manufacturing epoxy acrylic optical material KOC SOLUTION CO LTD 2015-04-29 CN disclosed
US-7709409-B2 Mixed catalytic composition CHEMTURA ORGANOMETALLICS GMBH (DE) 2010-05-04 US disclosed
US-7297804-B2 Catalytic composition of organotin compounds CHEMTURA ORGANOMETALICS GMBH (DE) 2007-11-20 US disclosed
US-20070179045-A1 Mixed catalytic composition PMC VLISSINGEN NETHERLANDS, B.V. (NL) 2007-08-02 US disclosed
US-20060052575-A1 Mixed catalyst composition CHEMTURA ORGANOMETALLICS GMBH (DE) 2006-03-09 US disclosed
US-20060047101-A1 Catalytic composition of organotin compounds CHEMTURA ORGANOMETALLICS GMBH (DE) 2006-03-02 US disclosed
EP-1567473-A1 MIXED CATALYTIC COMPOSITION Crompton GmbH (DE) 2005-08-31 EP disclosed
EP-1565509-A1 CATALYTIC COMPOSITION OF ORGANOTIN COMPOUNDS Crompton GmbH (DE) 2005-08-24 EP disclosed
EP-1541600-A1 Polymer dispersions with improved water-vapour barrier properties, their preparation and use in food coating Celanese Emulsions GmbH (DE) 2005-06-15 EP disclosed
US-20040236130-A1 Process for the preparation of trialkylsilated carboxylate monomers, the obatined trialkylsilated carboxylate monomers and their use in anti-fouling coatings SIGMA COATINGS B.V. (NL) 2004-11-25 US disclosed
WO-2004050742-A1 CATALYTIC COMPOSITION OF ORGANOTIN COMPOUNDS CROMPTON GMBH (DE) 2004-06-17 WO disclosed
WO-2004050597-A1 MIXED CATALYTIC COMPOSITION CROMPTON GMBH (DE) 2004-06-17 WO disclosed
EP-1389214-A1 PROCESS FOR THE PREPARATION OF TRIALKYLSILYLATED CARBOXYLATE MONOMERS, THE OBTAINED TRIALKYLSILYLATED CARBOXYLATE MONOMERS AND THEIR USE IN ANTI-FOULING COATINGS SIGMA COATINGS B.V. (NL) 2004-02-18 EP disclosed
WO-2002094838-A1 PROCESS FOR THE PREPARATION OF TRIALKYLSILYLATED CARBOXYLATE MONOMERS, THE OBTAINED TRIALKYLSILYLATED CARBOXYLATE MONOMERS AND THEIR USE IN ANTI-FOULING COATINGS SIGMA COATINGS B.V. (NL) 2002-11-28 WO disclosed
EP-1260513-A1 Process for the preparation of trialkylsilylated carboxylate monomers, the obtained trialkylsilylated carboxylate monomers and their use in antifouling coatings SIGMA COATINGS B.V. (NL) 2002-11-27 EP disclosed
US-5668244-A UNSATURATED EPOXIDES TOYO INK MANUFACTURING CO., LTD. (JP) 1997-09-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040236130-A1 Process for the preparation of trialkylsilated carboxylate monomers, the obatined trialkylsilated carboxylate monomers and their use in anti-fouling coatings ACMSD, OR10J3, CFD AKR1B1 1640/4885GPR84 1359/4885PPARG 3620/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.