Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.32 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.32 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2832316 | 1.00 | TSHR (0.49) | TSHRLMNAFAAHMAPTMAPK1 | |
| SCHEMBL1323802 | 1.00 | TSHR (0.49) | TSHRLMNAFAAHMAPTMAPK1 | |
| Iodide SCHEMBL28802516 | 0.98 | TSHR (0.47) | TSHRLMNAFAAHMAPTMAPK1 | |
| SCHEMBL2496829 | 0.98 | TSHR (0.46) | TSHRLMNAFAAHMAPTMAPK1 | |
| SCHEMBL222108 | 0.93 | TSHR (0.43) | TSHRLMNAFAAHTHRB | |
| Tetradecane SCHEMBL1083463 | 0.87 | TSHR (0.49) | TSHRLMNAFAAHMAPTMAPK1 | |
| SCHEMBL516498 | 0.86 | TSHR (0.41) | TSHRTHRB | |
| SCHEMBL28334362 | 0.86 | TSHR (0.47) | TSHRLMNAFAAHMAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL28879757 | 0.84 | TSHR (0.46) | TSHRLMNAFAAHMAPTMAPK1 | |
| Hexadecane SCHEMBL5163752 | 0.82 | TSHR (0.50) | TSHRLMNAFAAHMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6746711-B2 | REACTING A HYDROXYALKYLAMINE COMPOUND WITH METHYL(METH)ACRYLATE IN PRESENCE OF TRANSESTERIFICATION CATALYST WITH REMOVAL OF METHANOL BY-PRODUCT, FREE-RADICAL POLYMERIZING THE PRODUCT, ALKYLATING THE POLYMER | CLARIANT GMBH (DE) | 2004-06-08 | — | — | US | disclosed |
| US-20030191264-A1 | Reacting a hydroxyalkylamine compound with methyl(meth)acrylate in presence of transesterification catalyst with removal of methanol by-product, free-radical polymerizing the product, alkylating the polymer | CLARIANT GMBH | 2003-10-09 | — | — | US | disclosed |