SCHEMBL516498

SCHEMBL516498

C=C(C)C(=O)OC(C)N(CCC)CCC

nearest known ligand 0.41

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.41
ALDH1A1 P00352 2/20 0.35
THRB P10828 1/20 0.35
FDPS P14324 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL222108 0.89 TSHR (0.43) TSHRALDH1A1THRB
SCHEMBL2496829 0.88 TSHR (0.46) TSHRALDH1A1THRB
SCHEMBL6914196 0.86 TSHR (0.49) TSHRTHRB
SCHEMBL2832316 0.86 TSHR (0.49) TSHRTHRB
SCHEMBL1323802 0.86 TSHR (0.49) TSHRTHRB
Iodide SCHEMBL28802516 0.85 TSHR (0.47) TSHRTHRB
SCHEMBL28273631 0.85 TSHR (0.44) TSHRALDH1A1THRBFDPS
SCHEMBL14873 0.85 TSHR (0.44) TSHRALDH1A1THRBFDPS
Ammonia Solution, Strong SCHEMBL28263372 0.83 TSHR (0.42) TSHRALDH1A1THRB
Hydrochloric Acid SCHEMBL9258461 0.83 TSHR (0.42) TSHRALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 560 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3872573-B1 TONER ADDITIVE FORMULATION WITH CROSS-LINKED ORGANIC POLYMERIC ADDITIVE XEROX CORP (US) 2025-04-09 EP claimed
CN-119775480-A High-hardness self-cleaning antifouling resin and coating, and preparation method and application thereof 广东省科学院化工研究所 2025-04-08 CN claimed
US-12252568-B2 Silicone copolymer surface additive XEROX CORPORATION (US) 2025-03-18 US claimed
CN-116622351-B Carbon dioxide responsive nanoparticle as well as preparation method and application thereof 常州大学 2024-09-24 CN claimed
CN-117229440-A Preparation method and application of polymer carrier with twisted core structure 北京化工大学 2023-12-15 CN claimed
CN-113376980-B Titanium dioxide-free toner additive formulation with crosslinked organic polymer additive 施乐公司 2023-12-05 CN claimed
CN-116622351-A Carbon dioxide responsive nanoparticle as well as preparation method and application thereof 常州大学 2023-08-22 CN claimed
CN-115501205-B Radiotherapy sensitization nanoparticle and preparation method thereof 中国医学科学院放射医学研究所 2023-08-18 CN claimed
US-11717471-B2 Hydrogel microcapsules ISP INVESTMENTS LLC (US) 2023-08-08 US claimed
US-20230159683-A1 Silicone Copolymer Surface Additive XEROX CORPORATION 2023-05-25 US claimed
US-8663886-B2 Toner compositions and processes XEROX CORPORATION (US) 2014-03-04 US claimed
US-20130302392-A1 HYDROGEL MICROCAPSULES HERCULES LLC 2013-11-14 US claimed
EP-2646002-A2 HYDROGEL MICROCAPSULES Isp Investments Inc. (US) 2013-10-09 EP claimed
US-20120156606-A1 TONER COMPOSITIONS AND PROCESSES XEROX CORPORATION (US) 2012-06-21 US claimed
US-20120156605-A1 TONER COMPOSITIONS AND PROCESSES XEROX CORPORATION (US) 2012-06-21 US claimed
WO-2012075293-A2 HYDROGEL MICROCAPSULES ISP INVESTMENTS INC. (US) 2012-06-07 WO claimed
WO-2000016811-A2 MRI CONTRAST AGENT SCHERING AKTIENGESELLSCHAFT (DE) 2000-03-30 WO claimed
US-5069754-A Reinforcement with amphoteric polymer MITSUI-CYANAMID, LTD. (JP) 1991-12-03 US claimed
US-5047287-A Acrylonitrile-isoprene or butadiene/1,3-/ copolymer having amino group as adhesive TOYODA GOSEI CO., LTD. (JP) 1991-09-10 US claimed
US-4877687-A SURFACE TREATMENT WITH A QUATERNIZED ACRYLATED RESIN MITSUBISHI RAYON COMPANY, LTD. (JP) 1989-10-31 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11717471-B2 Hydrogel microcapsules MITF, DSG1, SHH TSHR 2621/4885ALDH1A1 1165/4885THRB 3065/4885
US-20130302392-A1 HYDROGEL MICROCAPSULES MITF, DSG1, SHH TSHR 2621/4885ALDH1A1 1165/4885THRB 3065/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.