Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | SCN4A | P35499 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL691646 | 1.00 | LTA4H (0.54) | LTA4HPKMGAAMCHR1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL30412643 | 0.99 | LTA4H (0.53) | LTA4HPKMGAAMCHR1SIGMAR1 | |
| SCHEMBL14033539 | 0.88 | LTA4H (0.52) | LTA4HMCHR1SIGMAR1BCHEMAOB | |
| SCHEMBL6076846 | 0.88 | MLNR (0.49) | LTA4H | |
| SCHEMBL5242188 | 0.86 | LTA4H (0.54) | LTA4HPKMGAASIGMAR1ACHE | |
| SCHEMBL5456925 | 0.86 | LTA4H (0.54) | LTA4HPKMGAASIGMAR1ACHE | |
| SCHEMBL25154290 | 0.85 | LTA4H (0.56) | LTA4HPKMGAASIGMAR1 | |
| SCHEMBL3626359 | 0.85 | LTA4H (0.56) | LTA4HPKMGAASIGMAR1 | |
| SCHEMBL3493009 | 0.85 | LTA4H (0.56) | LTA4HPKMGAASIGMAR1 | |
| SCHEMBL10674002 | 0.83 | LTA4H (0.54) | LTA4HPKMGAASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2421870-A2 | MODULATORS OF 5-HT RECEPTORS AND METHODS OF USE THEREOF | Abbott Laboratories (US) | 2012-02-29 | — | — | EP | disclosed |