SCHEMBL6914601

SCHEMBL6914601

CCCCCn1c(C(=O)Nc2ccc(C#N)cc2-c2nnn[nH]2)cc2ccccc21.CCCCn1c(C(=O)Nc2ccc(C#N)cc2-c2nnn[nH]2)cc2ccccc21

nearest known ligand 0.45

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 17/20 0.45
PTGDR2 Q9Y5Y4 1/20 0.38
ALDH1A1 P00352 1/20 0.37
TSHR P16473 1/20 0.37
HTT P42858 1/20 0.37
TRPA1 O75762 1/20 0.36
CNR1 P21554 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6713883 0.99 CNR2 (0.46) CNR2PTGDR2ALDH1A1TSHRHTT
SCHEMBL6711699 0.98 CNR2 (0.44) CNR2PTGDR2ALDH1A1TSHRHTT
SCHEMBL6709846 0.94 CNR2 (0.42) CNR2PTGDR2ALDH1A1TSHRHTT
SCHEMBL6711776 0.90 ROCK2 (0.39) CNR2PTGDR2ALDH1A1TSHRHTT
SCHEMBL6710061 0.89 CNR2 (0.45) CNR2ALDH1A1TSHRHTTTRPA1
SCHEMBL6710046 0.89 HDAC3 (0.41) CNR2ALDH1A1TSHRHTTTRPA1
SCHEMBL6708225 0.87 CNR2 (0.46) CNR2PTGDR2ALDH1A1TSHRHTT
SCHEMBL6708731 0.87 CNR2 (0.46) CNR2PTGDR2ALDH1A1TSHRHTT
SCHEMBL6710330 0.86 CNR2 (0.39) CNR2ALDH1A1TSHRHTTTRPA1
SCHEMBL6710237 0.86 CNR2 (0.42) CNR2PTGDR2ALDH1A1TSHRHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004018461-A2 ANTIBACTERIAL BENZOIC ACID DERIVATIVES PHARMACIA & UPJOHN COMPANY LLC (US) 2004-03-04 WO disclosed