Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 5/20 | 0.33 |
| ▸ | MAP3K14 | Q99558 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PPOX | P50336 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28555079 | 0.70 | — | — | |
| SCHEMBL2885125 | 0.70 | AHR (1.00) | AHRTP53LMNACYP2A6 | |
| SCHEMBL29588977 | 0.70 | AHR (1.00) | AHRTP53LMNACYP2A6 | |
| SCHEMBL11215846 | 0.70 | AHR (1.00) | AHRTP53LMNACYP2A6 | |
| SCHEMBL8518629 | 0.70 | CYP1A2 (0.38) | TP53CYP3A4ALDH1A1TDP1LMNA | |
| SCHEMBL6686721 | 0.70 | AHR (0.54) | AHRTP53HTR2CTSHRCYP3A4 | |
| SCHEMBL10922209 | 0.68 | AHR (0.52) | AHRTP53HTR2CALDH1A1TDP1 | |
| SCHEMBL3861110 | 0.67 | AHR (0.50) | AHRTP53HTR2CALDH1A1LMNA | |
| SCHEMBL6442096 | 0.67 | AHR (0.50) | AHRTP53HTR2CTSHRALDH1A1 | |
| SCHEMBL11858013 | 0.67 | TSHR (0.56) | AHRTP53HTR2CTSHRMAP3K14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004063229-A2 | TRANSITION METAL COMPLEXES IN THE CONTROLLED SYNTHESIS OF POLYOLEFINS SUBSTITUTED WITH FUNCTIONAL GROUPS | THE NIPPON SYNTHETIC CHEMICAL INDUSTRY CO., LTD. (JP) | 2004-07-29 | — | — | WO | disclosed |