Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | AHR | P35869 | 3/20 | 0.50 |
| ▸ | ALPG | P10696 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.39 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29561949 | 1.00 | TSHR (0.56) | TSHRAHRALPGALOX12ALOX15 | |
| SCHEMBL10922209 | 0.79 | AHR (0.52) | AHRALPGALOX12ALOX15KCNE1 | |
| SCHEMBL3861110 | 0.77 | AHR (0.50) | AHRALPGALOX12ALOX15KIF11 | |
| SCHEMBL6442096 | 0.77 | AHR (0.50) | TSHRAHRALPGALOX12ALOX15 | |
| SCHEMBL2762063 | 0.77 | ALDH1A1 (0.44) | TSHRAHRALDH1A1KDM4EHSD17B10 | |
| SCHEMBL16797674 | 0.75 | KCNE1 (0.42) | TSHRAHRKCNE1KCNQ1ALDH1A1 | |
| SCHEMBL8167005 | 0.74 | TSHR (0.59) | TSHRALOX12ALOX15KIF11ALDH1A1 | |
| SCHEMBL7519328 | 0.74 | TSHR (1.00) | TSHRALOX12ALOX15KIF11SMN1; SMN2 | |
| SCHEMBL16797671 | 0.74 | KCNE1 (0.44) | TSHRAHRKCNE1KCNQ1ALDH1A1 | |
| SCHEMBL25192586 | 0.73 | TSHR (0.56) | TSHRALOX12ALOX15KIF11ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113999263-B | Synthesis method of tri-substituted phosphine oxide compound | 苏州欣诺科生物科技有限公司 | 2022-04-01 | — | — | CN | claimed |
| CN-113999263-A | Synthesis method of tri-substituted phosphine oxide compound | 苏州欣诺科生物科技有限公司 | 2022-02-01 | — | — | CN | claimed |
| CN-113999263-B | Synthesis method of tri-substituted phosphine oxide compound | 苏州欣诺科生物科技有限公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-113999263-A | Synthesis method of tri-substituted phosphine oxide compound | 苏州欣诺科生物科技有限公司 | 2022-02-01 | — | — | CN | disclosed |
| US-3962281-A | METHOD OF PREPARING ALDEHYDES | SAGAMI CHEMICAL RESEARCH CENTER (JA) | 1976-06-08 | — | — | US | disclosed |