SCHEMBL69148

SCHEMBL69148

O=C(O)CN[C@H](CS)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.50
PTGS2 P35354 2/20 0.50
KDM4E B2RXH2 1/20 0.50
THRB P10828 1/20 0.50
ALOX15 P16050 1/20 0.50
NFKB1 P19838 1/20 0.50
THPO P40225 1/20 0.50
RECQL P46063 1/20 0.50
BLM P54132 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
FOLH1 Q04609 3/20 0.47
ACE P12821 2/20 0.45
PTGS1 P23219 2/20 0.40
GSTK1 Q9Y2Q3 1/20 0.40
SLC7A11 Q9UPY5 1/20 0.37
ALDH1A1 P00352 2/20 0.35
LMNA P02545 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
RIMKLA Q8IXN7 1/20 0.35
NAALAD2 Q9Y3Q0 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL80875 1.00 MAPT (0.50) MAPTPTGS2KDM4ETHRBALOX15
SCHEMBL197221 1.00 MAPT (0.50) MAPTPTGS2KDM4ETHRBALOX15
Ammonia Solution, Strong SCHEMBL19614510 0.98 MAPT (0.48) MAPTPTGS2KDM4ETHRBALOX15
Ammonia Solution, Strong SCHEMBL19614515 0.98 MAPT (0.48) MAPTPTGS2KDM4ETHRBALOX15
Cysteine SCHEMBL28399079 0.88 PTGS1 (0.59) MAPTPTGS2KDM4ETHRBALOX15
SCHEMBL929284 0.86 ACE (0.56) MAPTPTGS2KDM4ETHRBALOX15
SCHEMBL5904021 0.83
SCHEMBL4263217 0.83
SCHEMBL2284304 0.83
SCHEMBL7574384 0.82 MAPT (0.42) MAPTPTGS2KDM4ETHRBALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1630 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240131507-A1 TESTING FOR PARTICULATES HERO SCIENTIFIC LTD. (IL) 2024-04-25 US claimed
US-20230137741-A1 METHODS AND COMPOSITIONS FOR ANALYTE QUANTIFICATION MATTERWORKS INC 2023-05-04 US claimed
WO-2023070158-A1 METHODS FOR TREATING RESPIRATORY DISEASES MUCPharm Pty Ltd (AU) 2023-05-04 WO claimed
US-20210017488-A1 CELL CULTURE COMPOSITIONS WITH ANTIOXIDANTS AND METHODS FOR POLYPEPTIDE PRODUCTION GENENTECH, INC. (US) 2021-01-21 US claimed
EP-3712252-A1 CELL CULTURE COMPOSITIONS WITH ANTIOXIDANTS AND METHODS FOR POLYPEPTIDE PRODUCTION F. Hoffmann-La Roche AG (CH) 2020-09-23 EP claimed
CN-105264064-B O-phosphoserine export proteins and methods of producing O-phosphoserine using the same CJ第一制糖株式会社 2020-08-18 CN claimed
EP-3348567-B1 NOVEL O-PHOSPHOSERINE EFFLUX PROTEIN VARIANT AND METHOD FOR PRODUCING O-PHOSPHOSERINE, CYSTEINE AND DERIVATIVE THEREOF USING SAME CJ CHEILJEDANG CORP (KR) 2020-08-05 EP claimed
US-10687529-B2 Nematotoxic composition of synergistic effect, use of a nematotoxic composition of synergistic effect EMPRESA BRASILEIRA DE PESQUISA AGROPECUÁRIA-EMBRAPA (BR) 2020-06-23 US claimed
US-10676710-B2 Cell culture compositions with antioxidants and methods for polypeptide production GENENTECH, INC. (US) 2020-06-09 US claimed
CN-110951670-A Cell culture compositions with antioxidants and methods of polypeptide production 豪夫迈·罗氏有限公司 2020-04-03 CN claimed
US-4757066-A Reduces renal toxicity SANKYO COMPANY LIMITED (JP) 1988-07-12 US claimed
EP-0226304-A1 Composition containing a penem or carbapenem antibiotic SANKYO COMPANY LIMITED (JP) 1987-06-24 EP claimed
EP-0144519-B1 2',4'-DIFLUORO-4-HYDROXY-(1,1'-DIPHENYL)-3-CARBOXYLIC DERIVATIVES OF N-ACETYLCYSTEINE AND OF S-CARBOXYMETHYLCYSTEINE HAVING ANTI-INFLAMMATORY AND MUCOLYTIC ACTIVITY, PROCESS FOR THEIR PREPARATION AND RELATED PHARMACEUTICAL COMPOSITIONS LABORATORI GUIDOTTI S.P.A. (IT) 1987-06-10 EP claimed
EP-0209957-A1 Tablets containing S-carboxymethylcysteine CEDONA PHARMACEUTICALS B.V. (NL) 1987-01-28 EP claimed
WO-1984004924-A1 PURIFIED TRANSFORMING GROWTH FACTOR-BETA DERIVED FROM HUMAN PLATELETS AND PLACENTAS US COMMERCE (US) 1984-12-20 WO claimed
EP-0128849-A1 Purified transforming growth factor-beta derived from human platelets and placentas THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce (US) 1984-12-19 EP claimed
EP-0105014-A2 Repair of tissue in animals THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce (US) 1984-04-04 EP claimed
WO-1984001106-A1 REPAIR OF TISSUE IN ANIMALS US HEALTH (US) 1984-03-29 WO claimed
US-4288433-A THIOETHER AND A XANTHINE DERIVATIVE L'OREAL (FR) 1981-09-08 US claimed
US-4071517-A Soluble salts containing sulphur DUFOUR CLAUDE 1978-01-31 US claimed