Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.40 |
| ▸ | ACE | P12821 | 3/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22361657 | 1.00 | MAPT (0.42) | MAPTPTGS2BLMKDM4ETHRB | |
| SCHEMBL80875 | 0.82 | MAPT (0.50) | MAPTPTGS2BLMKDM4ETHRB | |
| SCHEMBL197221 | 0.82 | MAPT (0.50) | MAPTPTGS2BLMKDM4ETHRB | |
| SCHEMBL69148 | 0.82 | MAPT (0.50) | MAPTPTGS2BLMKDM4ETHRB | |
| Ammonia Solution, Strong SCHEMBL19614515 | 0.80 | MAPT (0.48) | MAPTPTGS2BLMKDM4ETHRB | |
| Ammonia Solution, Strong SCHEMBL19614510 | 0.80 | MAPT (0.48) | MAPTPTGS2BLMKDM4ETHRB | |
| SCHEMBL9636802 | 0.78 | PTGS1 (0.38) | MAPTPTGS2BLMKDM4ETHRB | |
| SCHEMBL9636795 | 0.78 | PTGS1 (0.38) | MAPTPTGS2BLMKDM4ETHRB | |
| SCHEMBL929284 | 0.78 | ACE (0.56) | MAPTPTGS2BLMKDM4ETHRB | |
| Zinc Ion SCHEMBL9455609 | 0.77 | MAPT (0.36) | MAPTPTGS2BLMKDM4ETHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0288151-B2 | Permanent wave composition | OREAL (FR) | 2002-10-02 | — | — | EP | disclosed |
| EP-0288151-B1 | Permanent wave composition | REDKEN LABORATORIES INC (US) | 1994-11-30 | — | — | EP | disclosed |
| US-4816246-A | AMMONIUM THIOGLYCOLATE | REDKEN LABORATORIES, INC. (US) | 1989-03-28 | — | — | US | disclosed |
| EP-0288151-A2 | Permanent wave composition | L'OREAL, S.A. (FR) | 1988-10-26 | — | — | EP | disclosed |