SCHEMBL6915410

SCHEMBL6915410

Nc1ncnc2c1ncn2[C@H]1C[C@H](O)[C@@H](COP(O)(O)=S)O1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 1/20 0.73
▸ P2RY1 P47900 5/20 0.69
▸ ENPP1 P22413 4/20 0.69
▸ P2RY2 P41231 3/20 0.57
▸ SRC P12931 2/20 0.57
▸ SMN1; SMN2 Q16637 2/20 0.57
▸ DNPH1 O43598 1/20 0.57
▸ PRKAB2 O43741 1/20 0.57
▸ TRPM2 O94759 1/20 0.57
▸ LDHA P00338 1/20 0.57
▸ ADRB2 P07550 1/20 0.57
▸ FBP1 P09467 1/20 0.57
▸ ADORA1 P30542 1/20 0.57
▸ PRKAG1 P54619 1/20 0.57
▸ PRKAA2 P54646 1/20 0.57
▸ PDE4D Q08499 1/20 0.57
▸ KCNH2 Q12809 1/20 0.57
▸ PRKAA1 Q13131 1/20 0.57
▸ PDE3A Q14432 1/20 0.57
▸ TAS1R3 Q7RTX0 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24059865 1.00 POLB (0.73) POLBP2RY1ENPP1P2RY2SRC
SCHEMBL20277576 1.00 POLB (0.73) POLBP2RY1ENPP1P2RY2SRC
SCHEMBL30969962 1.00 POLB (0.73) POLBP2RY1ENPP1P2RY2SRC
SCHEMBL20282944 1.00 POLB (0.73) POLBP2RY1ENPP1P2RY2SRC
SCHEMBL20276952 1.00 POLB (0.73) POLBP2RY1ENPP1P2RY2SRC
SCHEMBL4546151 0.91 POLB (0.81) POLBP2RY1ENPP1P2RY2SRC
SCHEMBL543475 0.91 POLB (0.81) POLBP2RY1ENPP1P2RY2SRC
SCHEMBL7882477 0.91 POLB (0.81) POLBP2RY1ENPP1P2RY2SRC
SCHEMBL18785113 0.91 POLB (0.81) POLBP2RY1ENPP1P2RY2SRC
SCHEMBL48174 0.91 POLB (0.81) POLBP2RY1ENPP1P2RY2SRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1620515-A Post-synthesis labeling of nucleic acids and uses thereof AMERSHAM BIOSCIENCES AB (SE) 2005-05-25 — — CN claimed
EP-1461455-A2 POST-SYNTHESIS LABELING OF NUCLEIC ACIDS AND USES THEREOF Amersham Biosciences AB (SE) 2004-09-29 — — EP claimed
WO-2003052115-A2 POST-SYNTHESIS LABELING OF NUCLEIC ACIDS AND USES THEREOF AMERSHAM BIOSCIENCES AB (SE) 2003-06-26 — — WO claimed
US-20030119005-A1 Post-synthesis labeling of nucleic acids, assays using nucleic acids that are labeled post-synthetically, single nucleotide polymorphism detection, and associated compounds and microarrays MOTOROLA, INC. 2003-06-26 — — US claimed
EP-4403042-A2 FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME Mars, Incorporated (US) 2024-07-24 — — EP disclosed
EP-3229612-B1 USE OF FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME MARS INC (US) 2024-06-26 — — EP disclosed
US-11185100-B2 Methods for modulating taste receptors MARS, INCORPORATED (US) 2021-11-30 — — US disclosed
EP-3229610-B1 FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME MARS INC (US) 2021-06-09 — — EP disclosed
US-20190021380-A1 FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME MARS, INCORPORATED (US) 2019-01-24 — — US disclosed
US-20180255813-A1 METHODS FOR MODULATING TASTE RECEPTORS MARS, INCORPORATED (US) 2018-09-13 — — US disclosed
US-20180168208-A1 FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME MARS, INCORPORATED (US) 2018-06-21 — — US disclosed
US-20180168208-A1 FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME MARS, INCORPORATED (US) 2018-06-21 — — US disclosed
EP-0731846-B1 NUCLEOSIDE ANALOGUE METHOD AMERSHAM PHARM BIOTECH UK LTD (GB) 1999-03-03 — — EP disclosed
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