Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.64 |
| ▸ | BCHE | P06276 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | MAOA | P21397 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.52 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11432402 | 1.00 | MAOB (0.64) | MAOBBCHEKMT2AMEN1CYP1B1 | |
| SCHEMBL10744598 | 0.94 | KMT2A (0.64) | MAOBBCHEKMT2AMEN1CYP1B1 | |
| SCHEMBL10744603 | 0.94 | KMT2A (0.64) | MAOBBCHEKMT2AMEN1CYP1B1 | |
| SCHEMBL6908275 | 0.94 | CYP1B1 (0.64) | MAOBBCHEKMT2AMEN1CYP1B1 | |
| SCHEMBL7922516 | 0.94 | CYP1B1 (0.64) | MAOBBCHEKMT2AMEN1CYP1B1 | |
| SCHEMBL9523424 | 0.92 | MAOB (0.61) | MAOBBCHEKMT2AMEN1CYP1B1 | |
| SCHEMBL5315888 | 0.92 | MAOB (0.61) | MAOBBCHEKMT2AMEN1CYP1B1 | |
| SCHEMBL15367534 | 0.92 | MAOB (0.61) | MAOBBCHEKMT2AMEN1CYP1B1 | |
| SCHEMBL17355377 | 0.92 | MAOB (0.61) | MAOBBCHEKMT2AMEN1CYP1B1 | |
| SCHEMBL9524097 | 0.87 | KMT2A (0.66) | MAOBBCHEKMT2AMEN1CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689899-B2 | HYDROGENATION OF THE CORRESPONDING DINITRO COMPOUNDS | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2004-02-10 | — | — | US | disclosed |
| US-20020019558-A1 | Diamine and acid anhydride | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2002-02-14 | — | — | US | disclosed |
| US-4182897-A | ENZYME INHIBITORS FOR PROTEOLYTIC ENZYMES | TORII & CO., LTD. (JP) | 1980-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020019558-A1 | Diamine and acid anhydride | CA1, ASIC1, CA4 | MAOB 1298/4885BCHE 2316/4885KMT2A 679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.