Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 6/20 | 0.46 |
| ▸ | CES2 | O00748 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 5/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 4/20 | 0.36 |
| ▸ | PPARD | Q03181 | 4/20 | 0.36 |
| ▸ | PPARA | Q07869 | 4/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.36 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.36 |
| ▸ | TLR2 | O60603 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6057358 | 0.96 | CES1 (0.42) | CES1CES2ALDH1A1TP53CA1 | |
| SCHEMBL3862259 | 0.96 | CES1 (0.42) | CES1CES2ALDH1A1TP53CA1 | |
| SCHEMBL9534599 | 0.93 | CES2 (0.48) | CES1CES2ALDH1A1TSHRAKR1B1 | |
| SCHEMBL2483865 | 0.92 | TSHR (0.48) | CES1CES2ALDH1A1TP53CA1 | |
| SCHEMBL5510815 | 0.91 | CES2 (0.50) | CES1CES2ALDH1A1TSHRPPARG | |
| SCHEMBL28817979 | 0.91 | CES2 (0.50) | CES1CES2ALDH1A1TSHRPPARG | |
| SCHEMBL27504162 | 0.91 | CES2 (0.50) | CES1CES2ALDH1A1TSHRPPARG | |
| SCHEMBL26121447 | 0.89 | CES1 (0.41) | CES1CES2ALDH1A1TP53CA1 | |
| SCHEMBL9743325 | 0.89 | CES1 (0.41) | CES1CES2ALDH1A1TP53CA1 | |
| SCHEMBL6067683 | 0.88 | CES1 (0.37) | CES1CES2ALDH1A1TP53CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6790932-B2 | TO BE USED IN THE LUBRICATED EXTRUSION WHEREIN ALSO LOW EXTRUSION PRESSURES CAN BE USED. | AUSIMONT S.P.A. (IT) | 2004-09-14 | — | — | US | claimed |
| US-5156589-A | Woven fabric coated with crosslinked polybutyl acrylate adhesive containing alkylphenyl polyethylene glycol and stabilizer | KARL OTTO BRAUN KG (DE) | 1992-10-20 | — | — | US | disclosed |
| US-4944958-A | COATED WOVEN FABRIC | KARL OTTO BRAUN KG (DE) | 1990-07-31 | — | — | US | disclosed |