Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 5/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.35 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6909440 | 0.81 | HMGCR (0.50) | HMGCRNR1I2LMNARECQLTSHR | |
| SCHEMBL6915809 | 0.80 | HMGCR (0.38) | HMGCRNR1I2LMNARECQLNR5A2 | |
| SCHEMBL6914237 | 0.80 | HMGCR (0.48) | HMGCRNR1I2LMNARECQLTSHR | |
| SCHEMBL6919061 | 0.80 | HMGCR (0.43) | HMGCRNR1I2LMNARECQLTSHR | |
| SCHEMBL9222249 | 0.78 | GAA (0.47) | HMGCRNR1I2LMNARECQLGAA | |
| SCHEMBL9222828 | 0.77 | HMGCR (0.41) | HMGCRNR1I2LMNARECQLTSHR | |
| SCHEMBL9227380 | 0.76 | HMGCR (0.48) | HMGCRNR1I2GPR55PTGS1PTGS2 | |
| SCHEMBL6917885 | 0.76 | HMGCR (0.53) | HMGCRNR1I2LMNARECQLGPR55 | |
| SCHEMBL1305322 | 0.75 | HMGCR (0.58) | HMGCRNR1I2LMNARECQLTSHR | |
| SCHEMBL6914648 | 0.75 | HMGCR (0.43) | HMGCRNR1I2LMNARECQLTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004026245-A2 | SUBSTITUTED PHOSPHONATE COMPOUNDS HAVING BONE ANABOLIC ACTIVITY | ILEX ONCOLOGY RESEARCH, SARL (CH) | 2004-04-01 | — | — | WO | claimed |