Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 4/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.34 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.33 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.33 |
| ▸ | GLRB | P48167 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6916388 | 0.80 | HMGCR (0.44) | HMGCRGPR55NR1I2LMNARECQL | |
| SCHEMBL9225348 | 0.80 | LMNA (0.43) | HMGCRGPR55NR1I2LMNARECQL | |
| SCHEMBL6910755 | 0.80 | GAA (0.49) | HMGCRGPR55NR1I2LMNARECQL | |
| SCHEMBL6916387 | 0.79 | LMNA (0.47) | HMGCRGPR55NR1I2LMNARECQL | |
| SCHEMBL6918005 | 0.79 | VCAM1 (0.40) | HMGCRGPR55NR1I2LMNARECQL | |
| SCHEMBL9224571 | 0.77 | GAA (0.49) | HMGCRLMNAGAAMEN1KMT2A | |
| SCHEMBL9224042 | 0.76 | GABBR2 (0.47) | HMGCRGPR55NR1I2LMNACA2 | |
| SCHEMBL6917719 | 0.75 | GABBR2 (0.52) | HMGCRGPR55NR1I2GABBR2GABBR1 | |
| SCHEMBL6918240 | 0.75 | GPR55 (0.37) | GPR55LMNARECQLCA2CA1 | |
| SCHEMBL9513470 | 0.74 | HMGCR (0.50) | HMGCRNR1I2LMNARECQLCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004026245-A2 | SUBSTITUTED PHOSPHONATE COMPOUNDS HAVING BONE ANABOLIC ACTIVITY | ILEX ONCOLOGY RESEARCH, SARL (CH) | 2004-04-01 | — | — | WO | claimed |