SCHEMBL6916446

SCHEMBL6916446

CS(=O)(=O)C1CCC(N=C=S)CC1

nearest known ligand 0.58

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
APLNR P35414 2/20 0.58
NAAA Q02083 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6916447 1.00 APLNR (0.58) APLNRNAAA
SCHEMBL3124187 0.77 APLNR (0.40) APLNRNAAA
SCHEMBL3124189 0.77 APLNR (0.40) APLNRNAAA
SCHEMBL289935 0.76
SCHEMBL3903198 0.76 APLNR (1.00) APLNRNAAA
SCHEMBL1965395 0.74
SCHEMBL23240196 0.70 APLNR (0.74) APLNRNAAA
SCHEMBL331120 0.70 APLNR (0.74) APLNR
Hydrochloric Acid SCHEMBL28118622 0.67
SCHEMBL710256 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004093995-A2 USE OF ANTIOXIDANTS TO TREAT BONE LOSS DISORDERS ST GEORGE'S ENTERPRISES LIMITED (GB) 2004-11-04 WO disclosed
US-RE36784-E Chemoprotective isothiocyanates THE JOHNS HOPKINS UNIVERSITY (US) 2000-07-18 US disclosed
US-5411986-A Chemoprotective isothiocyanates THE JOHNS HOPKINS UNIVERSITY (US) 1995-05-02 US disclosed