Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ELANE | P08246 | 3/20 | 0.43 |
| ▸ | CTRC | Q99895 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL563659 | 0.95 | ALOX15 (0.54) | ALDH1A1GAAMEN1KMT2AKDM4E | |
| SCHEMBL6910732 | 0.93 | MAPT (0.56) | ALDH1A1GAAMEN1KMT2AKDM4E | |
| SCHEMBL6907126 | 0.93 | MAPT (0.56) | ALDH1A1GAAMEN1KMT2AKDM4E | |
| SCHEMBL6911155 | 0.93 | MAPT (0.56) | ALDH1A1GAAMEN1KMT2AKDM4E | |
| SCHEMBL6912499 | 0.93 | MAPT (0.56) | ALDH1A1GAAMEN1KMT2AKDM4E | |
| SCHEMBL6912180 | 0.93 | MAPT (0.56) | ALDH1A1GAAMEN1KMT2AKDM4E | |
| SCHEMBL6914193 | 0.93 | MAPT (0.56) | ALDH1A1GAAMEN1KMT2AKDM4E | |
| SCHEMBL6905774 | 0.93 | MAPT (0.56) | ALDH1A1GAAMEN1KMT2AKDM4E | |
| SCHEMBL6913197 | 0.93 | MAPT (0.56) | ALDH1A1GAAMEN1KMT2AKDM4E | |
| SCHEMBL6916585 | 0.93 | MAPT (0.56) | ALDH1A1GAAMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018552-A1 | USE OF COMPOSITIONS CONTAINING 4-HYDROXY-2-PYRONES FOR STABILISING ORGANIC PLASTICS CONTAINING HALOGEN | REAGENS DEUTSCHLAND GMBH (DE) | 2004-03-04 | — | — | WO | disclosed |
| US-6114546-A | Aminomethylene derivatives and ultraviolet absorbent comprising thereof | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 2000-09-05 | — | — | US | disclosed |
| CN-1236357-A | Aminomethylene derivatives and ultraviolet absorber comprising the same | CHEMIPRO KASEI KAISHA LTD (JP) | 1999-11-24 | — | — | CN | disclosed |
| EP-0950655-A1 | AMINOMETHYLENE DERIVATIVES AND ULTRAVIOLET ABSORBER COMPRISING THE SAME | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 1999-10-20 | — | — | EP | disclosed |
| EP-0572455-A1 | SUBSTITUTED PYRIDINONES AND PYRIMIDINONES AS ANGIOTENSIN II ANTAGONISTS | Astra Pharmaceuticals Limited (GB) | 1993-12-08 | — | — | EP | disclosed |
| CN-1068109-A | New angiotension II antagonists and the preparation of preparation and application | FISONS PLC (GB) | 1993-01-20 | — | — | CN | disclosed |
| WO-1992014714-A1 | SUBSTITUTED PYRIDINONES AND PYRIMIDINONES AS ANGIOTENSIN II ANTAGONISTS | FISONS PLC (GB) | 1992-09-03 | — | — | WO | disclosed |
| EP-0500297-A1 | Substituted pyridinones and pyrimidinones as angiotensin II antagonists | FISONS plc (GB) | 1992-08-26 | — | — | EP | disclosed |
| US-4745116-A | INHIBITORS OF SERINE PROTEASE | SYNTEX (U.S.A.) INC. (US) | 1988-05-17 | — | — | US | disclosed |