SCHEMBL6916647

SCHEMBL6916647

Nc1cccc(N)n1.Nc1nc(N)nc(N)n1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS2 P35228 3/20 0.55
NOS3 P29474 2/20 0.55
ASIC3 Q9UHC3 1/20 0.48
ADORA2A P29274 2/20 0.46
ADORA1 P30542 2/20 0.46
POLB P06746 1/20 0.46
ADORA3 P0DMS8 1/20 0.46
ADORA2B P29275 1/20 0.46
RAB9A P51151 2/20 0.41
GRM4 Q14833 1/20 0.41
BACE1 P56817 3/20 0.40
NCF1 P14598 2/20 0.40
PLAU P00749 1/20 0.39
KDM4E B2RXH2 1/20 0.39
ALOX15 P16050 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
NOS1 P29475 1/20 0.39
PI4KA P42356 1/20 0.39
PI4K2B Q8TCG2 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL64599 0.90
SCHEMBL6917729 0.87 HSP90AA1 (0.46) NOS2NOS3ASIC3ADORA2AADORA1
Hydrochloric Acid SCHEMBL8446392 0.87 NOS2 (0.60) NOS2NOS3ASIC3POLBRAB9A
SCHEMBL3743328 0.87
SCHEMBL28747612 0.87
Hydrochloric Acid SCHEMBL5681195 0.87
SCHEMBL27937485 0.87
Ammonia Solution, Strong SCHEMBL10709860 0.87 NOS2 (0.60) NOS2NOS3ASIC3GRM4BACE1
Methyl Alcohol SCHEMBL29137692 0.81 NOS2 (0.62) NOS2NOS3ASIC3GRM4BACE1
SCHEMBL28695346 0.79 NOS2 (0.52) NOS2NOS3ASIC3GRM4BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6753406-B2 MELTING POLYBUTYLENE TEREPHTHALATE IN PRESENCE OF STABILIZER (CALCIUM STEARATE AND/OR MELAMINE); RECYCLING, POLLUTION CONTROL TICONA GMBH (DE) 2004-06-22 US claimed
US-20030125514-A1 Process and means for reducing formaldehyde emission during the processing of thermoplastics with admixed polyacetal TICONA GMBH (DE) 2003-07-03 US claimed